Roberto Bernabei

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CONTEXT Criteria for potentially inappropriate medication use among elderly patients have been used in the past decade in large US epidemiological surveys to identify populations at risk and specifically target risk-management strategies. In contrast, in Europe little information is available about potentially inappropriate medication use and is based on(More)
OBJECTIVE To describe the results of an international trial of the home care version of the MDS assessment and problem identification system (the MDS-HC), including reliability estimates, a comparison of MDS-HC reliabilities with reliabilities of the same items in the MDS 2.0 nursing home assessment instrument, and an examination of the types of problems(More)
Frailty is a clinical state in which there is an increase in an individual's vulnerability for developing increased dependency and/or mortality when exposed to a stressor. Frailty can occur as the result of a range of diseases and medical conditions. A consensus group consisting of delegates from 6 major international, European, and US societies created 4(More)
OBJECTIVES To determine the prevalence of adverse drug reaction (ADR)-related hospital admissions in an older population, to describe the most common clinical manifestations and drugs most frequently responsible for ADR-related hospital admissions, and to identify independent factors predictive of these ADRs. DESIGN Multicenter pharmacoepidemiology survey(More)
OBJECTIVE To study the incidence and the risk factors of adverse drug reactions. DESIGN Multicenter survey. SETTING Hospitalized care: 22 internal medicine and 19 geriatric wards. PATIENTS All patients (n = 9,148) consecutively admitted during two observation periods of 2 months. MAIN OUTCOME MEASURE Incidence of adverse drug reactions. RESULTS(More)
CONTEXT Cancer pain can be relieved with pharmacological agents as indicated by the World Health Organization (WHO). All too frequently pain management is reported to be poor. OBJECTIVE To evaluate the adequacy of pain management in elderly and minority cancer patients admitted to nursing homes. DESIGN Retrospective, cross-sectional study. SETTING A(More)
PURPOSE Cognitive impairment is an exceedingly prevalent condition among patients with heart failure, independently associated with disability and mortality. However, the determinants of cognitive dysfunction associated with heart failure are still unclear. We assessed the correlates of cognitive impairment among patients with heart failure enrolled in a(More)
BACKGROUND Optimal care for frail elderly patients depends on comprehensive assessment. This is especially true in the complex setting of interdisciplinary home care programs. To facilitate comprehensive assessment, as well as to generate a useful, policy-relevant patient database, standardized, multidimensional, and validated instruments are very helpful.(More)
OBJECTIVE To evaluate the impact of a programme of integrated social and medical care among frail elderly people living in the community. DESIGN Randomised study with 1 year follow up. SETTING Town in northern Italy (Rovereto). SUBJECTS 200 older people already receiving conventional community care services. INTERVENTION Random allocation to an(More)
BACKGROUND Reality orientation therapy combined with cholinesterase inhibitors has not been evaluated in patients with Alzheimer's disease. AIMS To perform such an evaluation. METHOD We randomly assigned 79 of 156 patients treated with donepezil to receive a reality orientation programme. Caregivers of the treatment group were trained to offer the(More)