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In this paper an optimal solution to the problem of determining both vehicle attitude and position using line-of-sight measurements is presented. The new algorithm is derived from a generalized predictive filter for nonlinear systems. This uses a one time-step ahead approach to propagate a simple kinematics model for attitude and position determination. The(More)
The massive use of Next-Generation Sequencing (NGS) technologies is uncovering an unexpected amount of variability. The functional characterization of such variability, particularly in the most common form of variation found, the Single Nucleotide Variants (SNVs), has become a priority that needs to be addressed in a systematic way. VARIANT (VARIant ANalyis(More)
Genome browsers have gained importance as more genomes and related genomic information become available. However, the increase of information brought about by new generation sequencing technologies is, at the same time, causing a subtle but continuous decrease in the efficiency of conventional genome browsers. Here, we present Genome Maps, a genome browser(More)
Babelomics has been running for more than one decade offering a user-friendly interface for the functional analysis of gene expression and genomic data. Here we present its fifth release, which includes support for Next Generation Sequencing data including gene expression (RNA-seq), exome or genome resequencing. Babelomics has simplified its interface,(More)
Genomic experiments (e.g. differential gene expression, single-nucleotide polymorphism association) typically produce ranked list of genes. We present a simple but powerful approach which uses protein-protein interaction data to detect sub-networks within such ranked lists of genes or proteins. We performed an exhaustive study of network parameters that(More)
The objective of this paper is to develop a robust and efficient approach for relative navigation and attitude estimation of spacecraft flying in formation. The approach developed here uses information from a new optical sensor that provides a line of sight vector from the master spacecraft to the secondary satellite. The overall system provides a novel,(More)
Transcription factors (TFs) and miRNAs are the most important dynamic regulators in the control of gene expression in multicellular organisms. These regulatory elements play crucial roles in development, cell cycling and cell signaling, and they have also been associated with many diseases. The Regulatory Network Analysis Tool (RENATO) web server makes the(More)
We prove the NP-completeness of a problem, we call Social Group Commonality (SGC), which queries the commonality amongst the objects 'touched' by a collections of agents while executing an action. Although it naturally arises in several contexts, e.g., to profile the behaviour of a collection of system users, SGC has, to the authors' knowledge, been(More)
This paper presents a robust and efficient approach for relative navigation and attitude estimation of spacecraft flying in formation. This approach uses measurements from a new optical sensor that provides a line of sight vector from the master spacecraft to the secondary satellite. The overall system provides a novel, reliable, and autonomous relative(More)