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Computed tomography has proved very valuable in the diagnosis of central nervous system changes in tuberous sclerosis. A full analysis of the CT findings in 34 cases is presented. Intracranial calcifications — periventricular, corticosubcortical, within the white substance or in the posterior cranial fossa — were the most frequent finding, followed by(More)
To explore the prescription patterns of erythropoiesis-stimulating agents (ESAs) in four large Italian geographic areas, where different health policy interventions to promote biosimilar use in routine care are undertaken. A retrospective drug utilization study was conducted during the years 2009–2013. The data sources were the administrative databases of(More)
BACKGROUND Since 2007 biosimilars of erythropoiesis-stimulating agents (ESAs) are available on the Italian market. Very limited post-marketing data exist on the comparative effectiveness of biosimilar and originator ESAs. AIM This population-based study was aimed to compare the effects of biosimilars, reference product and other ESAs still covered by(More)
Granulocyte colony-stimulating factors (G-CSFs) are biological products for which the main indication of use is chemotherapy-induced neutropenia. Biosimilars of G-CSFs have been available in Europe since 2007. The objective of this study was to investigate the prescribing pattern of G-CSFs in five Italian centres using different healthcare policy(More)
This retrospective observational study was based on databases of the Local Health Authority of Treviso, Italy. It evaluated the prevalence and the effectiveness of oral anticoagulation treatment (OAT) for the management of nonvalvular atrial fibrillation (NVAF) in everyday clinical practice. Out of 6,138 NVAF patients, only 3,024 received vitamin K(More)
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