Roberta McKean

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Vision is a sensation that is created from complex processes and provides uswith a representation of the world around us. There are many important aspects of vision, but visual acuity was judged to be the most appropriate vision assessment for the NIH Toolbox for Assessment of Neurological and Behavioral Function, both because of its central role in visual(More)
The degradation of klerval (I) was studied as a function of pH. The extent and routes of degradation were found to be pH-dependent. Under strongly acidic conditions (pH<2), the drug predominantly undergoes specific acid-catalyzed hydrolysis of the side-chain amide bond yielding II8), the drug undergoes specific base-catalyzed hyrolysis yielding II and(More)
Partial trisomy for the short arm of chromosome No. 5 appears to result in an identifiable syndrome. Major features include characteristic facial appearance, mental and growth retardation, seizures, and an excess of ulnar loops. Less certain features may include strabismus and an absence of major congenital malformations. The translocation present in this(More)
Fibroblast growth factors are a series of well characterized proteins that have intriguing pharmacological properties. Acidic fibroblast growth factor (aFGF) recently appeared in the literature for its efficacy in spinal cord repair in rats. The protein has proven difficult to analyze by capillary electrophoresis, because it has a tendency to unfold,(More)
Cross-correlation was implemented for flow-injection analysis by using two parallel flow lines, each with amperometric detectors, and driven by peristaltic pumps. One flow line was used to generate the reference signal for an analog correlator circuit and the other to generate the analyte signal. Cross-correlation was performed by multiplying these signals(More)
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