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Parametric design systems model a design as a constrained collection of schemata. Designers work in such systems at two levels: definition of schemata and constraints; and search within a schema collection for meaningful instances. Propagation-based systems yield efficient algorithms that are complete within their domain, require explicit specification of a(More)
It has been shown in scattered reports (1, 2, 3, 4) from this laboratory that sudden changes of intrathoracic and abdominal pressure such as occur in coughing and straining produce simultaneous changes in the arterial pressure and in cerebrospinal pressure. It was argued that whereas these pressure changes may strain the arteries of the arms, legs and skin,(More)
Bovine capillary and microvessel pericytes were grown in monolayer in standard tissue culture medium supplemented with 10% newborn calf serum at various oxygen tensions for up to ten weeks. The pericytes synthesized alkaline phosphatase and formed colonies that mineralized. Energy dispersive X-ray spectrometry revealed the presence of calcium and phosphate,(More)
BACKGROUND AND DESIGN The ability of superficial dermabrasion to improve clinical features of photoaged skin is well known, but the specific biological mechanisms involved are poorly understood. The so-called repair zone, as visualized by routine histologic examination, has been attributed to new collagen formation within the papillary dermis and may be(More)
Nowadays, numerous Computer-aided Design (CAD) software packages support Building Information Modeling (BIM). BIM software can benefit of advanced simulation in the pre-design phase of construction projects. In this case, we show focus on models of the emergency evacuation regarding the security and safety. We analyze the evacuation simulation of a model(More)
Building Information Modeling (BIM) and its open standard Industry Foundation Classes (IFC) are becoming popular in the design phase in the Architecture and Construction industry. Here, we focus on integrating BIM and DEVS (Discrete Event systems Specification) simulation of occupancy analysis. We present a case study for Copenhagen's New Elephant House,(More)