Robert W. Rho

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INTRODUCTION Electrical isolation of the pulmonary veins (PVs) to treat paroxysmal atrial fibrillation (AF) has been described using "entry block" as an endpoint for PV isolation. We describe a new technique for guiding PV isolation, using "exit block" out of the PV after ablation as a criterion for successful isolation. METHODS AND RESULTS A circular(More)
OBJECTIVES The purpose of this study was to objectively quantify the similarity of 12-lead electrocardiogram (ECG) waveforms using two quantitative metrics, the correlation coefficient (CORR) and the mean absolute deviation (MAD). BACKGROUND Comparison of the 12-lead ECG morphology between ventricular tachycardia (VT) and a pace-map is frequently(More)
Arrhythmias occur commonly in patients after cardiac surgery. Atrial fibrillation is the most common arrhythmia in the postoperative period; it accounts for significant morbidity to the patient and prolonged hospital stays, and it contributes significantly to the cost of hospitalization. It occurs more commonly in elderly men and in patients undergoing(More)
Atrial fibrillation (AF) is a significant cause of morbidity and health care expenditures. Patients with AF suffer a variety of symptoms including chest pain, palpitations, shortness of breath, and fatigue. Some patients have no symptoms, a condition referred to as asymptomatic or "silent" AF. Asymptomatic AF has significant clinical implications. Patients(More)
INTRODUCTION Pulmonary vein (PV) triggers initiate atrial fibrillation (AF). The aim of this study was to compare the outcome of focal PV ablation versus targeted PV electrical isolation aided by multipolar catheter recordings in the coronary sinus (CS) and right atrium and magnetic electroanatomic mapping (MEAM) for drug-refractory AF. METHODS AND(More)
Background: There is compelling evidence that coronary atherosclerosis represents a chronic active process characterized by inflammation, impaired flbrinolysis, intermittent plaque rupture, and luminal thrombosis. Identifying readily measurable plasma markers of procoagulant activity may have an important role in both tracking and understanding the natural(More)
BACKGROUND Whether sex differences in implantable cardioverter-defibrillator (ICD) benefit exist remains unanswered. We evaluated sex differences in mode of death among a large cohort of ambulatory heart failure patients who meet criteria for a primary prevention ICD. METHODS AND RESULTS Patients from 5 trials or registries were included if they met(More)
BACKGROUND Patients with a left ventricular assist device (LVAD) as a bridge to heart transplantation (HT) often have elevated levels of panel reactive antibodies (PRA). The clinical significance of anti-human histocompatibility leukocyte antigen (HLA) antibodies detected by flow cytometry in PRA negative patients remains unclear. METHODS Eighteen(More)
Sudden death claims 250,000 lives annually in the U.S. The vast majority of such events are due to ventricular fibrillation and ventricular tachycardia. Even though these arrhythmias can be converted if treated promptly, less than 5% of victims of out-of-hospital cardiac arrest survive to hospitalization. This poor survival is often due to delay in the(More)
Cardiac resynchronization therapy (CRT) is a new and promising therapeutic option for patients with severe heart failure and intraventricular conduction delay. Patients who are candidates for CRT and have a previously implanted device may utilize a "Y" IS 1 connector to accommodate the coronary sinus lead. This modification has the potential to alter(More)