Robert Wütschert

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Adverse skin reactions to low molecular weight heparins (LMWH) are rare even though their true incidence is probably underestimated because of under-reporting. These reactions may occur as an urticarial rash, presumably due to local histamine release or have the features of a classic type I immediate hypersensitivity reaction. They can also present as skin(More)
Pneumatic intermittent compression is an effective method to prevent postoperative venous thromboembolism. Its efficacy has been ascribed to both a haemodynamic action (increase of blood flow velocity) and a stimulation of endogenous fibrinolytic activity [via the production of tissue-type plasminogen activator (t-PA) by the vascular endothelium]. The(More)
BACKGROUND The efficacy of wearing compression stockings on clinical vessel disappearance following sclerotherapy of telangiectasias and reticular veins has been a matter of debate for half a century. OBJECTIVE To determine the relative efficacy of compression following sclerotherapy and to determine its impact on general quality of life in a prospective(More)
OBJECTIVE To study the accuracy of the measurement of TcPo2 for the determination of the optimal level of amputation in patients with end-stage vascular disease (i.e., the level at which the reamputation rate and the proportion of too-proximal amputations will be minimized). RESEARCH DESIGN AND METHODS We used a Medline literature search of all published(More)
BACKGROUND The Second European Consensus Document on Chronic Critical Leg Ischemia defined criteria to predict healing of leg ulcers. These recommendations are based on selected studies but the true performances of the tests proposed are not stated. METHODS We performed an electronic and manual literature search to retrieve all studies that included the(More)
Antithrombotic agents are frequently used in patients with peripheral arterial occlusive disease. This use is based on controlled clinical trials but also (mainly) on empirical experience of clinicians or on extrapolation from data obtained in coronary patients. The present paper reviews briefly the indications of anti-platelet and anticoagulant treatments(More)
Peripheral arterial disease of the lower limbs is a manifestation of atherosclerosis, and may also affect other vascular territories such as the coronary and cerebral arteries. Progressive narrowing of the vessels up to total occlusion can present as intermittent claudication or pain at rest, with or without cutaneous lesions. Patients with intermittent(More)
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