Filter Results:
- Full text PDF available (70)
Publication Year
1974
2018
- This year (8)
- Last 5 years (38)
- Last 10 years (56)
Publication Type
Co-author
Journals and Conferences
Learn More
- Oscar Puig, Michael T Marr, M Laure Ruhf, Robert Tjian
- Genes & development
- 2003
The Drosophila insulin receptor (dInR) regulates cell growth and proliferation through the dPI3K/dAkt pathway, which is conserved in metazoan organisms. Here we report the identification and… (More)
- Nicole King, Matthew Westbrook, +33 authors Daniel Rokhsar
- Nature
- 2008
Choanoflagellates are the closest known relatives of metazoans. To discover potential molecular mechanisms underlying the evolution of metazoan multicellularity, we sequenced and analysed the genome… (More)
We show that the activities of two Ets-related transcription factors required for normal eye development in Drosophila, pointed and yan, are regulated by the Ras1/MAPK pathway. The pointed gene codes… (More)
- M D Rabenstein, Sharleen X Zhou, John T Lis, Robert Tjian
- Proceedings of the National Academy of Sciences…
- 1999
The TATA box-binding protein (TBP) is an essential component of the RNA polymerase II transcription apparatus in eukaryotic cells. Until recently, it was thought that the general transcriptional… (More)
Drosophila TATA-box-binding protein (TBP)-related factor 2 (TRF2) is a member of a family of TBP-related factors present in metazoan organisms. Recent evidence suggests that TRF2s are required for… (More)
- Raymond H. Jacobson, Andreas G Ladurner, D. King, Robert Tjian
- Science
- 2000
TFIID is a large multiprotein complex that initiates assembly of the transcription machinery. It is unclear how TFIID recognizes promoters in vivo when templates are nucleosome-bound. Here, it is… (More)
- James A. Goodrich, Tim Hoey, C J Thut, Arie Admon, Robert Tjian
- Cell
- 1993
Enhancement of RNA polymerase II transcription by the viral transactivator VP16 requires the TFIID complex, which consists of the TATA-binding protein (TBP) and TBP-associated factors (TAFs). Here we… (More)
- Paul J Mitchell, Robert Tjian
- Science
- 1989
The cloning of genes encoding mammalian DNA binding transcription factors for RNA polymerase II has provided the opportunity to analyze the structure and function of these proteins. This review… (More)
- Michael Levine, Robert Tjian
- Nature
- 2003
Whole-genome sequence assemblies are now available for seven different animals, including nematode worms, mice and humans. Comparative genome analyses reveal a surprising constancy in genetic… (More)
- Oscar Puig, Robert Tjian
- Genes & development
- 2005
The insulin signaling pathway, which is conserved in evolution from flies to humans, evolved to allow a fast response to changes in nutrient availability while keeping glucose concentration constant… (More)