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The cold dark matter model has become the leading theoretical picture for the formation of structure in the Universe. This model, together with the theory of cosmic inflation, makes a clear prediction for the initial conditions for structure formation and predicts that structures grow hierarchically through gravitational instability. Testing this model(More)
The cold dark matter model has become the leading theoretical paradigm for the formation of structure in the Universe. Together with the theory of cosmic inflation, this model makes a clear prediction for the initial conditions for structure formation and predicts that structures grow hierarchically through gravitational instability. Testing this model(More)
We discuss the design and implementation of a parallel adaptive P 3 M code, for massively parallel architectures. The code, although primarily designed for conducting gravitational simulations in a cosmological context, also includes a Smoothed Particle Hydrodynamics solver. The code is written in a combination of C, FORTRAN 77 and FORTRAN 90. The MPI-2(More)
BACKGROUND Duchenne muscular dystrophy results from mutation of the dystrophin gene, causing skeletal and cardiac muscle loss of function. The mdx mouse model of Duchenne muscular dystrophy is widely utilized to evaluate the potential of therapeutic regimens to modulate the loss of skeletal muscle function associated with dystrophin mutation. Importantly,(More)
Cross-presentation of cell-associated antigens (Ag) plays an important role in the induction of anti-tumor responses, autoimmune diseases, and transplant rejection. While several dendritic cell (DC) populations can induce pro-inflammatory CD8(+) T cell responses to cell-associated Ag during infection, in the absence of infection, cross-priming of naïve(More)
  • Tue, Oct, Colin Morrison, Robert Thacker, Charla Del Mes, Richard Cooke +1 other
  • 2015
Though caterpillars of the moth Periphoba arcaei will eat a wide variety of plants, they have also evolved a defense mechanism previously only seen in insects that specialize on eating toxic plants. They incorporate toxins from the tropical plant Vismia baccifera and advertise their unpal-atability with brilliant green bodies covered in toxin-tipped hairs.(More)
  • Daniel Abeyta Salazar, Susan E, Place, Dean Fairbanks, Mark Stemen, Paul Melcon +26 others
  • 2012
iii ACKNOWLEDGEMENTS This piece of work is dedicated to my family and friends who have helped me along the path to attaining a meaningful education. I especially would like to thank my parents for their moral support and understanding of the importance of what I have accomplished. My mother, Vicki Salazar, has played a monumental role as someone who has(More)
This thesis has been read by each member of the following supervisory committee and by majority vote has been found to be satisfactory. I have read the thesis of Robert Thacker in its nal form and have found that (1) its format, citations, and bibliographic style are consistent and acceptable; (2) its illustrative materials including gures, tables, and(More)