Robert Szarka

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This study examines the intranasal instillation of lipopolysaccharide (LPS) into BALB/c mice causing acute pulmonary damage, due to neutrophil infiltration and sepsis. A dose response with LPS showed that an intranasal instillation of 167 microg/ml (10 microg/mouse) caused acute lung injury within 2-4 h and reached maximal damage at 24-48 h. We found the(More)
Brefeldin A, a fungal metabolite which interrupts trafficking of proteins via the Golgi by causing disassembly of the Golgi stacks, has been used to investigate the mechanism of movement of phosphatidylethanolamine (PtdEtn) from its sites of synthesis to the cell surface. PtdEtn is made in hepatocytes by two major pathways, (a) from CDP-ethanolamine on the(More)
Parathyroid cysts were found in 2-5% of beef steers and heifers while collecting parathyroids at a local abattoir. The cyst fluid contained parathyroid hormone (PTH), averaging 15 ng/ml of fluid. Reversed-phase high-performance liquid chromatographic (HPLC) analysis of the fluid using an acetonitrile-trifluoroacetic acid solvent system, followed by(More)
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