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We introduce a set of techniques for haptically manipulating digital media such as video, audio, voicemail and computer graphics, utilizing virtual mediating dynamic models based on intuitive physical metaphors. For example, a video sequence can be modeled by linking its motion to a heavy spinning virtual wheel: the user browses by grasping a physical(More)
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This paper describes a new technique for the synthesis of musical sounds which we have named Scanned Synthesis. Scanned Synthesis is based on the psychoacoustics of how we hear and appreciate timbres and on our motor control (haptic) abilities to manipulate timbres during live performance. A unique feature of scanned synthesis is its emphasis on the(More)
This paper presents a design for a randomized, placement-insensitive, data cache and analyzes its performance. An address stream is randomized using a hash function which selects a set in an associative cache. The manipulation of large data structures is modeled by traversal of a cyclic sweep address sequence and the miss ratio is accurately determined for(More)
Genome-wide association study (GWAS) has identified genetic variants in the promoter region of the high temperature requirement factor A1 (HTRA1) gene associated with age-related macular degeneration (AMD). As a secreted serine protease, HTRA1 has been reported to interact with members of the transforming growth factor-β (TGF-β) family and regulate their(More)
BACKGROUND The "ABCs of Diabetes" are defined as hemoglobin A1c < 7.0%, blood pressure < 130/80 millimeters mercury (mm Hg), and lowdensity lipoprotein cholesterol (LDL-C) < 100 milligrams per deciliter (mg per dL). Assessments of 3-part goal attainment of A1c, blood pressure, and cholesterol have been reported using data from the National Health and(More)