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AMG has recently completed the development of the AMG SPEEDSHIFT DCT. For development and test of the control software AMG used a novel test method based on a test case generator, and a software-in-the-loop (SiL) setup used to run the DCT control software in closed loop on a Windows PC. In this paper, we motivate and describe the corresponding test process… (More)
The signal transducer and activator of transcription molecules (Stats) play key roles in cytokine-induced signal transduction. Recently, it was proposed that constitutively activated Stat 3 (Stat 3 phosphorylated) contributes to the pathogenesis of multiple myeloma (MM) by preventing apoptosis and inducing proliferation. The study aim was to investigate… (More)
It has been shown that okadaic acid (OA) diminishes insulin secretion of rat pancreatic islets in response to glucose, glyceraldehyde and KCl. Glucose, glyceraldehyde and KCl cause release of insulin by depolarization and subsequent opening of L-type calcium channels. Calcium entry into cells is thought to be related to protein phosphorylation. To evaluate… (More)
The 1993 chair of the Health and Human Services' Workgroup for Electronic Data Interchange's Financial Implications Technical Advisory Group predicts big savings from EDI under the Clinton healthcare reform plan. A cost/benefit analysis by the TAG foresees net cumulative savings from EDI of $42 billion by the turn of the century.