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- Robert S. Eisenberg
- The Journal of Membrane Biology
- 1996

Predicting function from structure is a goal as old as molecular biology, indeed biology itself: the first glimpse of the anatomy of an animal, like the first glimpse of the anatomy of a protein,â€¦ (More)

Stochastic trajectories are described that underly classical diffusion between known concentrations. The description of those experimental boundary conditions requires a phase space using the fullâ€¦ (More)

- Duan P. Chen, Robert S. Eisenberg
- Biophysical journal
- 1993

Flux through an open ionic channel is analyzed with Poisson-Nernst-Planck (PNP) theory. The channel protein is described as an unchanging but nonuniform distribution of permanent charge, the chargeâ€¦ (More)

- Robert S. Eisenberg, Peter W. Gage
- The Journal of general physiology
- 1969

The resting ionic conductances of frog sartorius muscle fibers have been determined in a variety of conditions in order to measure the potassium conductance of the tubular and surface membranesâ€¦ (More)

- Igor Kh Kaufman, Dmitri Georgivich Luchinsky, Rodrique Tindjong, Peter V. E. McClintock, Robert S. Eisenberg
- Physical biology
- 2013

We report self-consistent Brownian dynamics simulations of a simple electrostatic model of the selectivity filters (SF) of calcium ion channels. They reveal regular structure in the conductance andâ€¦ (More)

- D. P. Chen, Joseph W. Jerome, Robert S. Eisenberg, Victor Barcilon
- SIAM Journal of Applied Mathematics
- 1997

Poisson-Nernst-Planck (PNP) systems are considered in the case of vanishing permanent charge. A detailed case study, based on natural categories described by system boundary conditions and flux, isâ€¦ (More)

- Richard T. Mathias, James L. Rae, Robert S. Eisenberg
- Biophysical journal
- 1981

The effective intracellular resistivity Ri of the ocular lens is a measure of the coupling between cells. Since degradation of coupling may accompany cataracts, measurements of Ri are of considerableâ€¦ (More)

- Igor Kh. Kaufman, Dmitry G. Luchinsky, Rodrique Tindjong, Peter V. E. McClintock, Robert S. Eisenberg
- Physical review. E, Statistical, nonlinear, andâ€¦
- 2013

We use Brownian dynamics (BD) simulations to study the ionic conduction and valence selectivity of a generic electrostatic model of a biological ion channel as functions of the fixed charge Q(f) atâ€¦ (More)

- Zeev Schuss, Boaz Nadler, Robert S. Eisenberg
- Physical review. E, Statistical, nonlinear, andâ€¦
- 2001

Permeation of ions from one electrolytic solution to another, through a protein channel, is a biological process of considerable importance. Permeation occurs on a time scale of micro- toâ€¦ (More)

- Dirk Gillespie, Wolfgang Nonner, Robert S. Eisenberg
- Physical review. E, Statistical, nonlinear, andâ€¦
- 2003

An approximate electrostatic (ES) excess free energy functional for charged, hard sphere fluids is presented. This functional is designed for systems with large density variations, but may also beâ€¦ (More)