Robert S. Lees

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Anopheles arabiensis Patton (Diptera: Culicidae) larvae were reared from hatching to the adult stage in the laboratory under a range of diet and larval concentrations using a factorial design. The range circumscribed most of the larval densities and diet concentrations that would allow larval growth and survival using the particular diet formulation and(More)
Arterial diameter estimation from X-ray ciné angiograms is important for quantifying coronary artery disease (CAD) and for evaluating therapy. However, diameter measurement in vessel cross sections < or =1.0 mm is associated with large measurement errors. We present a novel diameter estimator which reduces both magnitude and variability of measurement(More)
Transmural concentration profiles of 125I-albumin in vivo were measured across the normal and balloon catheter-deendothelialized rabbit descending thoracic aorta as a function of time following intravenous injection. A tracer was injected 5 or 60 minutes after deendothelialization, and the animals were sacrificed after circulation times of 10, 30 or 60(More)
Thermal analysis of human plasma low density lipoproteins reveals a broad reversible transition encompassing body temperature. The calorimetric and x-ray scattering data identify this transition as a cooperation, liquid-crystalline to liquid phase change involving the cholesterol esters in the lipoprotein. This behavior requires the presence of a region(More)
Atherosclerosis causes heterogeneous remodeling of arterial structure and composition in the carotid vessel wall. It has been shown that the progression of the disease can be monitored by tracking changes in the carotid intima-media thickness (IMT). Non-invasive peripheral vascular ultrasound (U/S) of the carotid artery is a non-invasive, cost effective,(More)
Noninvasive methods for diagnosis of carotid and vertebrobasilar disease may be divided into passive techniques and those in which the body is interrogated by the introduction of some sort of signal such as an ultrasound beam. Older techniques have been of limited value, whereas newer noninvasive methods can give specific, accurate, and quantitative(More)
To determine whether damaged arterial wall selectively accumulates lipoproteins, normocholesterolemic rabbits were injected with human radiolabeled low density lipoproteins, high density lipoproteins, and/or albumin 24 hr to 12 weeks after balloon-catheter de-endothelialization of the abdominal aorta. When 125I-labeled low density lipoproteins and(More)