Robert S. Kirk

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The effectiveness and efficiency of the nation' s freight transportation system depend on reliable data to inform decisions at all levels of government and in the private sector—accurate data on goods movement are needed to address issues involving congestion, economic competitiveness, safety and security, and the environment. The expert committee that(More)
BACKGROUND The human epidermal growth factor receptor (EGFR) is an important therapeutic target in oncology, and three different types of EGFR inhibitors have been approved for the treatment of cancer patients. However, there has been no clear association between the expression levels of EGFR protein in the tumours determined by the FDA-approved EGFR(More)
High-level functional (or behavioral) simulation models are difficult, time-consuming, and expensive to develop. We report on a method for automatically generating the program code for a high-level functional simulation model. The high-level model is produced directly from the program code for the circuit components' functional models and a netlist(More)
Transportation Research Board publications are available by ordering individual publications directly from the TRB Business Office, through the Internet at or, or by annual subscription through organizational or individual affiliation with TRB. Affiliates and library subscribers are eligible for substantial discounts.(More)
Focusing especially on the later stages of the design task, when a complete (or nearly so) design is being optimized at the structural level prior to final physical layout, we identify some aspects of the VLSI domain which complicate efficient design both for human and machine agents. We describe a simple but useful idea and a prototype implemented system(More)
The Airport Improvement Program (AIP) has been providing federal grants for airport development and planning since the passage of the Airport and Airway Improvement Act of 1982 (P.L. 97-248). AIP funding is usually spent on projects that support aircraft operations such as runways, taxiways, aprons, noise abatement, land purchase, and safety or emergency(More)