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First decade findings on the impacts of organic matter removal and soil compaction are reported for the 26 oldest installations in the nationwide network of long-term soil productivity sites. Complete removal of surface organic matter led to declines in soil C concentration to 20 cm depth and to reduced nutrient availability. The effect is attributed mainly(More)
This article formulates the multidimensional nuclear Overhauser effect spectroscopy (NOESY) interpretation problem using graph theory and presents a novel, bottom-up, topology-constrained distance network analysis algorithm for NOESY cross peak interpretation using assigned resonances. AutoStructure is a software suite that implements this(More)
One of the most important challenges in modern protein NMR is the development of fast and sensitive structure quality assessment measures that can be used to evaluate the "goodness-of-fit" of the 3D structure with NOESY data, to indicate the correctness of the fold and accuracy of the resulting structure. Quality assessment is especially critical for(More)
Large amounts of data from high-throughput metabolomic experiments are commonly visualized using a principal component analysis (PCA) two-dimensional scores plot. The question of the similarity or difference between multiple metabolic states then becomes a question of the degree of overlap between their respective data point clusters in principal component(More)
We assessed the direct and indirect effect of the herbicide glyphosate on soil microbial communities from ponderosa pine (Pinus ponderosa) plantations of varying site quality. Direct, toxic effects were tested using culture media and soil bioassays at glyphosate concentrations up to 100-fold greater than expected following a single ®eld application.(More)
The impact of forest management operations on soil physical properties is important to understand, since management can significantly change site productivity by altering root growth potential, water infiltration and soil erosion , and water and nutrient availability. We studied soil bulk density and strength changes as indicators of soil com-paction before(More)
We tested three disturbance hypotheses in young conifer plantations: H 1 : soil compaction and removal of surface organic matter produces sustained changes in microbial community size, activity, and structure in mineral soil; H 2 : microbial community characteristics in mineral soil are linked to the recovery of plant diversity; and H 3 : community(More)
Sequestering carbon (C) in forest soils can benefit site fertility and help offset greenhouse gas emissions. However, identifying soil conditions and forest management practices which best promote C accumulation remains a challenging task. We tested whether soil incorporation of masticated woody residues alters short-term C storage at forested sites in(More)
Parkinson's disease (PD) is a multifactorial disorder with a complex etiology including genetic risk factors, environmental exposures, and aging. While energy failure and oxidative stress have largely been associated with the loss of dopaminergic cells in PD and the toxicity induced by mitochondrial/environmental toxins, very little is known regarding the(More)
Rapid and accurate functional assignment of novel proteins is increasing in importance, given the completion of numerous genome sequencing projects and the vastly expanding list of unannotated proteins. Traditionally, global primary-sequence and structure comparisons have been used to determine putative function. These approaches, however, do not emphasize(More)