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  • Zenzo Isogai, Robert N. Ono, +7 authors Lynn Y Sakai
  • Biology, Medicine
  • The Journal of Biological Chemistry
  • 2003 (First Publication: 24 January 2003)
  • Latent transforming growth factor β-binding protein 1 (LTBP-1) targets latent complexes of transforming growth factor β to the extracellular matrix, where the latent cytokine is subsequentlyExpand
  • Robert N. Ono, Gerhard Sengle, +9 authors Lynn Y Sakai
  • Biology, Medicine
  • The Journal of Biological Chemistry
  • 2009 (First Publication: 6 April 2009)
  • Latent transforming growth factor (TGF) β-binding proteins (LTBPs) interact with fibrillin-1. This interaction is important for proper sequestration and extracellular control of TGFβ. Surface plasmonExpand
  • Gerhard Sengle, Robert N. Ono, Takako Sasaki, Lynn Y Sakai
  • Medicine, Biology
  • The Journal of biological chemistry
  • 2011 (First Publication: 18 February 2011)
  • The specific functions of the prodomains of TGFβ superfamily members are largely unknown. Interactions are known between prodomains of TGFβ-1-3 and latent TGFβ-binding proteins and between prodomainsExpand
  • Zenzo Isogai, Anders Aspberg, Douglas R Keene, Robert N. Ono, Dieter P. Reinhardt, Lynn Y Sakai
  • Biology, Medicine
  • The Journal of Biological Chemistry
  • 2002 (First Publication: 8 February 2002)
  • Fibrillin-containing microfibrils are polymeric structures that are difficult to extract from connective tissues. Proteolytic digestion of tissues has been utilized to release microfibrils for study.Expand