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Effect of dialysis dose and membrane flux in maintenance hemodialysis.
- G. Eknoyan, G. Beck, +17 authors Robert M Toto
- The New England journal of medicine
- 19 December 2002
BACKGROUND The effects of the dose of dialysis and the level of flux of the dialyzer membrane on mortality and morbidity among patients undergoing maintenance hemodialysis are uncertain. METHODS We… Expand
Angiotensin-converting enzyme inhibitors and progression of nondiabetic renal disease. A meta-analysis of patient-level data.
PURPOSE To examine the efficacy of ACE inhibitors for treatment of nondiabetic renal disease. DATA SOURCES 11 randomized, controlled trials comparing the efficacy of antihypertensive regimens… Expand
Progression of Chronic Kidney Disease: The Role of Blood Pressure Control, Proteinuria, and Angiotensin-Converting Enzyme Inhibition: A Patient-Level Meta-Analysis
Context Guidelines recommend a blood pressure of less than 130/80 mm Hg for patients with chronic kidney disease. Contribution This meta-analysis showed that systolic blood pressure and urinary… Expand
The risk of developing end-stage renal disease in patients with type 2 diabetes and nephropathy: the RENAAL study.
BACKGROUND Diabetic nephropathy has become the single most important cause of end-stage renal disease (ESRD) worldwide. Strategies to slow the rate of loss of renal function in these patients have… Expand
Proteinuria and other markers of chronic kidney disease: a position statement of the national kidney foundation (NKF) and the national institute of diabetes and digestive and kidney diseases (NIDDK).
Dialysis dose and the effect of gender and body size on outcome in the HEMO Study.
BACKGROUND Gender and body size have been associated with survival in hemodialysis populations. In recent observational studies, overall mortality was similar in men and women and higher in small… Expand
Risk scores for predicting outcomes in patients with type 2 diabetes and nephropathy: the RENAAL study.
- W. Keane, Z. Zhang, +11 authors B. Brenner
- Clinical journal of the American Society of…
- 1 July 2006
Diabetic nephropathy is the most important cause of ESRD. The aim of this study was to develop a risk score from risk predictors for ESRD, with and without death, in the Reduction of Endpoints in… Expand
Angiotensin-Converting Enzyme Inhibitors and Progression of Nondiabetic Renal Disease
Chronic renal disease is a major public health problem in the United States. According to the 1999 Annual Data Report of the U.S. Renal Data System, more than 357 000 people have end-stage renal… Expand
Arachidonic acid epoxygenase: detection of epoxyeicosatrienoic acids in human urine.
- Robert M Toto, A. Siddhanta, S. Manna, B. Pramanik, J. Falck, J. Capdevila
- Chemistry, Medicine
- Biochimica et biophysica acta
- 2 June 1987
Epoxyeicosatrienoic acids, metabolites of the cytochrome P-450-mediated epoxygenase reaction, were detected in human urine by gas chromatographic-mass spectroscopic techniques after conversion to… Expand
Differential effects of calcium channel blockers on size selectivity of proteinuria in diabetic glomerulopathy.
BACKGROUND Calcium channel blockers (CCBs) are known to have differential effects on both changes in proteinuria as well as progression of diabetic nephropathy. No clinical study, however, has… Expand