Robert M. Sharpe

Learn More
The aim of this review is first, to provide the clinical anaesthetist with a sufficient background regarding evoked responses, and second, to present current research in this sphere, thereby allowing an appraisal to be made of the usefulness of evoked potentials in the clinical setting. We shall consider: (1) the background, including the origins of the(More)
We have studied in 12 patients the effect of desflurane in nitrous oxide on the electroencephalogram (EEG) and the early cortical auditory evoked response (AER). After induction with desflurane, patients' lungs were ventilated to maintain three different end-expiratory concentrations of desflurane (1.5, 3 and 6%) during four consecutive 10-min periods(More)
We have studied the effect of a bolus dose of midazolam on the auditory evoked response (AER) of the electroencephalogram (EEG) in nine patients. We measured the AER in the awake patient, at the point of loss of the eyelash reflex and when airway support was required. The eyelash reflex was lost at mean 1.78 (SD 0.5) min after administration of the(More)
Female rats reared in unisexual (U) or bisexual (B) cross-fostered litters were mated at 75 days of age and their maternal behaviour compared by periodic observation over 20 days following birth of their litters. In two separate experiments, U-females showed a lower incidence of pregnancy and, at birth, of litters with ten or more pups than B-females (P(More)
Low power, radarlike electromagnetic (EM) wave sensors, operating in a homodyne interferometric mode, are being used to measure tissue motions in the human vocal tract during speech. However, when these and similar sensors are used in front of the laryngeal region during voiced speech, there remains an uncertainty regarding the contributions to the sensor(More)
We have studied the effect of bolus doses of alfentanil on the arousal response to intubation, using the auditory evoked response (AER) of the electroencephalogram (EEG) in 45 anaesthetized patients. After induction of anaesthesia with propofol and 20 min of positive pressure ventilation via a laryngeal mask airway with 0.6 MAC of isoflurane and 50%(More)
Higher-order basis functions have been constructed for surface-based differential forms that are used in engineering simulations. These surface-based forms have been designed to complement the volume-based forms present in EMSolve , a finite element code. The basis functions are constructed on a reference element and transformed, as necessary, for each(More)