Robert M Schiller

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Afamily physician meets a new patient, who complains of frequent headaches and back stiffness, and is now concerned about frequent episodes of colds and cough. The patient uses a variety of herbs, and has seen an acupuncturist, without much improvement. He is increasingly concerned by his symptoms, and wants to use his health insurance to cover any further(More)
Glucosamine is one of the most popular dietary supplements sold in the United States. Most clinical trials have focused on its use in osteoarthritis of the knee. The reported adverse effects have been relatively well studied and are generally uncommon and minor. No significant supplement-drug interactions involving glucosamine have been reported. The(More)
Enhanced alpha-aminoisobutyric acid transport by hamster cells cultured in the absence of D-glucose has been demonstrated in isolated membrane vesicles. The observed enhancement was seen in the presence but not in the absence of Na+. Kinetic analysis of transport using both the intact cells and the membrane vesicles showed that the overall enhancement was(More)
In cultured hamster cells starved for glucose for 24 hr there is an enhancement of the rate of alpha-aminoisobutyric acid transport ("shiftup"). When the starved cells are re-fed with glucose, the rate of transport shifts back down to the low, "regulated" rate typical of cells continuously fed with medium containing glucose ("shiftdown"). The high,(More)
Plasma membrane fractions isolated from mouse fibroblast BALB/c 3T3 cells transformed by simian virus 40 were partially purified by treatment with dimethylmaleic anhydride followed by extraction with 2% cholate. The extracted proteins were combined with exogenous phospholipids and eluted through a Sephadex G50 column. Reconstituted vesicles thus obtained(More)