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Analysis of flavivirus NS5 methyltransferase cap binding.

• Brian J. Geiss, Aaron A. Thompson, +4 authors Olve B. Peersen
• Journal of molecular biology
• 2009

The flavivirus 2'-O-nucleoside N-terminal RNA methyltransferase (MTase) enzyme is responsible for methylating the viral RNA cap structure. To increase our understanding of the mechanism of viral RNA… (More)

Essential Function of Dicer in Resolving DNA Damage in the Rapidly Dividing Cells of the Developing and Malignant Cerebellum.

• Vijay Swahari, Ayumi Nakamura, +7 authors Mohanish Deshmukh
• Cell reports
• 2016

Maintenance of genomic integrity is critical during neurodevelopment, particularly in rapidly dividing cerebellar granule neuronal precursors that experience constitutive replication-associated DNA… (More)

Dysregulated miRNA biogenesis downstream of cellular stress and ALS-causing mutations: a new mechanism for ALS.

• Anna Emde, Chen Eitan, +16 authors Eran Hornstein
• The EMBO journal
• 2015

Interest in RNA dysfunction in amyotrophic lateral sclerosis (ALS) recently aroused upon discovering causative mutations in RNA-binding protein genes. Here, we show that extensive down-regulation of… (More)

MicroRNA circulating in the early aftermath of motor vehicle collision predict persistent pain development and suggest a role for microRNA in sex-specific pain differences.

• Sarah D Linnstaedt, Margaret G. Walker, +14 authors Samuel A McLean
• Molecular pain
• 2015

BACKGROUND Molecular mediators influencing the transition from acute to persistent musculoskeletal pain following common stress exposures such as motor vehicle collision (MVC) remain poorly… (More)

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