Robert L. Obenchain

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BACKGROUND Urinary incontinence is a highly prevalent and burdensome condition among women. However, fewer than half of women with symptoms talk to a physician about incontinence, and the determinants of treatment seeking are not well understood. DESIGN A two-stage cross-sectional survey of adult U.S. women; 45,000 households participating in NFO(More)
OBJECTIVE The purpose of this study was to better understand the subjective bothersomeness of stress urinary incontinence symptoms and their impact on the quality of life of community-dwelling women. STUDY DESIGN We conducted a mail survey of 605 women in the United States who reported symptoms of stress urinary incontinence. RESULTS More than three(More)
UNLABELLED Schizophrenia leads to impairments in mental, social, and physical functioning, which should be included in evaluations of treatment. OBJECTIVES This study was designed to determine the reliability and validity of the Medical Outcomes Study Short Form Health Survey (SF-36) for schizophrenic patients, to characterize perceived functioning and(More)
OBJECTIVE To determine if the type of antidepressant drug is related to adherence to National Committee for Quality Assurance (NCQA) Antidepressant Medication Management (AMM) quality measures and to assess the 6-month health care costs among newly diagnosed depressed patients. METHODS The MarketScan Commercial Claims and Encounter database for medical(More)
The objective of this study was to evaluate the effectiveness of duloxetine in improving quality of life among women with stress and mixed urinary incontinence. The study included 451 women with self-reported stress incontinence episodes (≥1/week) who were randomized to duloxetine (40 mg BID) or placebo in a double-blind, usual care design. Patients and(More)
BACKGROUND Statistical models based on item response theory were used to examine (a) the performance of individual Positive and Negative Syndrome Scale (PANSS) items and their options, (b) the effectiveness of various subscales to discriminate among individual differences in symptom severity, and (c) the appropriateness of cutoff scores recently recommended(More)
OBJECTIVES To determine the extent to which women with incontinence have been identified by physicians, the coping and treatment strategies that incontinent women use, and the factors associated with treatment strategy utilization. STUDY DESIGN A 2-stage, nationwide, cross-sectional survey. METHODS Survey participants were adult women from(More)
In this study, we describe 'bootstrap' methodology for placing statistical confidence limits around an incremental cost effectiveness ratio (ICER). This approach was applied to a retrospective study of annual charges for patients undergoing pharmacotherapy for depression. We used MarketScanSM (service mark) data from 1990 to 1992, which includes medical and(More)
OBJECTIVE Four groups of patients receiving different antidepressant drugs in a primary care setting were compared in terms of duration of antidepressant therapy and health and mental health care utilization and costs. METHODS A retrospective analysis of the medical and pharmacy claims of an employed population and their families was conducted. A total of(More)
Background: The economic costs of depression are significant, both the direct medical costs of care and the indirect costs of lost productivity. Empirical studies of antidepressant costeffectiveness suggest that the use of selective serotonin reuptake inhibitors (SSRI) may be no more costly than tricyclic antidepressants (TCA), will improve tolerability,(More)