Robert L. Hannan

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To evaluate the relationship between postoperative serum lactate levels and outcome in children undergoing open heart surgery. Prospective, noninterventional study. Pediatric intensive care unit (PICU) of a university hospital. 41 nonconsecutive children who had had cardiopulmonary bypass for repair of congenital heart disease. None. Serum lactate levels(More)
Hypoxic states are associated with abnormal proliferation and constriction of the smooth muscle cells surrounding the distal vessels of the lung. In hypoxic as well as in normal states, the endothelial cell layer may play a key role in controlling smooth muscle tone by secreting a number of vasoactive agents. Platelet-derived growth factor (PDGF), produced(More)
BACKGROUND Atrial fibrillation is a common complication of cardiovascular surgery. Beta-blockers have been shown to decrease the incidence of postoperative atrial fibrillation. However, the use of magnesium is more controversial. It was our hypothesis that adjunctive magnesium sulfate would improve the efficacy of beta-blockers alone in the prevention of(More)
BACKGROUND We developed a novel mechanical rapid cardiopulmonary support system (CPS) in 1996 to eliminate what we believed were shortcomings of conventional extracorporeal membrane oxygenation (ECMO) circuits when used in patients with congenital heart disease. We reviewed the use of this system over a nine year period to determine if we had been(More)
BACKGROUND With emphasis today on cost containment in health care, the results and costs of cardiac operations in elderly patients are being scrutinized. METHODS Our computerized database was used to obtain the characteristics of patients undergoing cardiac operations from January 1990 to July 1994. A study group of 628 patients aged 70 years and over was(More)
BACKGROUND We sought to determine if postoperative serial lactate determinations follow predictable patterns that could be useful in directing management, especially the initiation of postoperative mechanical cardiopulmonary support (CPS). METHODS Eight patients undergoing CPS in a 2-year period and 147 patients not requiring postoperative CPS in 6 months(More)
BACKGROUND We report a single-institution experience using a collaborative surgical and catheter-based approach to the initial treatment of pulmonary atresia with intact ventricular septum. METHODS A retrospective review was conducted of all neonates admitted with pulmonary atresia with intact ventricular septum from 1996 to March 2007. RESULTS We(More)
AIM To determine the efficacy and safety of a continuous subcutaneous local anesthetic (LA) infusion in pediatric patients following open heart surgery. BACKGROUND The use of a continuous LA infusion has been shown to be beneficial following adult cardiac surgery. To date there are no studies in the pediatric population. METHODS/MATERIALS Using a(More)