Robert L. Grubb

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PURPOSE To assess retrospectively the clinical accuracy of an magnetic resonance imaging-guided robotic prostate biopsy system that has been used in the US National Cancer Institute for over 6 years. METHODS Series of 2D transverse volumetric MR image slices of the prostate both pre (high-resolution T2-weighted)- and post (low-resolution)- needle(More)
Chemoprevention of prostate cancer is a laudable and desirable goal. One strategy for chemoprevention is androgen deprivation therapy with 5␣-reductase inhibitors, such as finasteride and dutas-teride (1 , 2). The recent landmark Prostate Cancer Prevention Trial (PCPT), which used finasteride, was the first phase III clinical trial of prostate cancer(More)
Among genitourinary malignancies, bladder cancer (BCa) ranks second in both prevalence and cause of death. Biomarkers of BCa for diagnosis, prognosis and disease surveillance could potentially help prevent progression, improve survival rates and reduce health care costs. Among several oncogenic signaling pathways implicated in BCa progression is that of(More)
OBJECTIVE The accuracy and precision of resection with awake brain mapping is augmented when combined with frameless stereotaxy. Frameless stereotactic assisted surgery, however, typically involves immobilization in Mayfield pins. Rigid fixation, however, may be problematic for individuals undergoing awake craniotomy. We describe an alternate method of(More)
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