Robert K Richards

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In developing a high-performance liquid chromatographic assay for thiopental [5-ethyl-5-(1-methylbutyl)-2-thiobarbituric acid], a thiopental isomer [5-ethyl-5-(1-ethylpropyl)-2-thiobarbituric acid] was found. This isomer occurs (6-7%) in supposedly pure thiopental and in the commercially available thiopental sodium administered to patients for induction of(More)