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ELM—the database of eukaryotic linear motifs

• Holger Dinkel, Sushama Michael, +26 authors Toby J. Gibson
• Nucleic Acids Research
• 2012

Linear motifs are short, evolutionarily plastic components of regulatory proteins and provide low-affinity interaction interfaces. These compact modules play central roles in mediating every aspect… (More)

The eukaryotic linear motif resource ELM: 10 years and counting

• Holger Dinkel, Kim Van Roey, +17 authors Toby J. Gibson
• Nucleic Acids Research
• 2014

The eukaryotic linear motif (ELM http://elm.eu.org) resource is a hub for collecting, classifying and curating information about short linear motifs (SLiMs). For >10 years, this resource has provided… (More)

Attributes of short linear motifs.

• Norman E. Davey, Kim Van Roey, +7 authors Toby J. Gibson
• Molecular bioSystems
• 2012

Traditionally, protein-protein interactions were thought to be mediated by large, structured domains. However, it has become clear that the interactome comprises a wide range of binding interfaces… (More)

ELM: the status of the 2010 eukaryotic linear motif resource

• Cathryn M. Gould, Francesca Diella, +20 authors Toby J. Gibson
• Nucleic Acids Research
• 2010

Linear motifs are short segments of multidomain proteins that provide regulatory functions independently of protein tertiary structure. Much of intracellular signalling passes through protein… (More)

A Highly Conserved Program of Neuronal Microexons Is Misregulated in Autistic Brains

• Manuel Irimia, Robert J. Weatheritt, +14 authors Benjamin J. Blencowe
• Cell
• 2014

Alternative splicing (AS) generates vast transcriptomic and proteomic complexity. However, which of the myriad of detected AS events provide important biological functions is not well understood.… (More)

Classification of Intrinsically Disordered Regions and Proteins

• Robin van der Lee, Marija Buljan, +15 authors M. Madan Babu
• Chemical reviews
• 2014

Robin van der Lee,*,†,‡ Marija Buljan,†,▲ Benjamin Lang,†,▲ Robert J. Weatheritt,†,▲ Gary W. Daughdrill, A. Keith Dunker, Monika Fuxreiter, Julian Gough, Joerg Gsponer, David T. Jones, Philip M. Kim,… (More)

Short linear motifs: ubiquitous and functionally diverse protein interaction modules directing cell regulation.

• Kim Van Roey, Bora Uyar, +5 authors Norman E. Davey
• Chemical reviews
• 2014

Interaction Modules Directing Cell Regulation Kim Van Roey,† Bora Uyar,† Robert J. Weatheritt,‡ Holger Dinkel,† Markus Seiler,† Aidan Budd,† Toby J. Gibson,† and Norman E. Davey*,†,§ †Structural and… (More)

Executive control of spatial attention shifts in the auditory compared to the visual modality.

• Katrin Krumbholz, Esther A Nobis, Robert J. Weatheritt, Gereon R. Fink
• Human brain mapping
• 2009

Voluntary orienting of visual spatial attention has been shown to be associated with activation in a distributed network of frontal and parietal brain areas. Neuropsychological data suggest that at… (More)

Linear motifs confer functional diversity onto splice variants

• Robert J. Weatheritt, Norman E. Davey, Toby J. Gibson
• Nucleic acids research
• 2012

The pre-translational modification of messenger ribonucleic acids (mRNAs) by alternative promoter usage and alternative splicing is an important source of pleiotropy. Despite intensive efforts, our… (More)

Asymmetric mRNA localization contributes to fidelity and sensitivity of spatially localized systems

• Robert J. Weatheritt, Toby J. Gibson, M. Madan Babu
• Nature Structural &Molecular Biology
• 2014

Although many proteins are localized after translation, asymmetric protein distribution is also achieved by translation after mRNA localization. Why are certain mRNA transported to a distal location… (More)

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