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A web-based authoring tool, developed using VaNTH CAPE technology, is used to construct innovative online assignments that provide students with real time formative feedback as they attempt to solve quantitative engineering problems. The interactive system has found favor with instructors, teaching assistants and students. Because each step taken by the(More)
Further understanding of the mechanisms involved in cellular and intracellular delivery of transgene is needed to produce clinical applications of gene therapy. The compartmental and computational model designed in this work is integrated with data from previous experiments to quantitatively estimate rate constants of plasmid translocation across cellular(More)
An introductory physiological transport course was recently redesigned to take advantage of the benefits of challenge-based instruction. In this mode of instruction a series of specific challenges are introduced throughout the semester. The challenges are based on real problems in biotransport and are designed to motivate students to discover a solution.(More)
Many courses adopt a traditional approach to instruction, characterized by lectures that follow a linear progression through a textbook that is organized about the general taxonomy of the subject matter. New theories of learning suggest that this taxonomy-driven instruction offers fewer opportunities for students to develop their problem solving abilities(More)
Steady-state lymph-to-plasma concentration ratios (L/Ps) of neutral dextrans, cationic DEAE dextrans, and endogenous proteins were determined under normal and increased permeability conditions in six unanesthetized yearling sheep prepared with chronic lung lymph fistulas. Fluorescent dextrans with radii ranging from 1 to 30 nm were intravenously infused,(More)
abstract This paper presents the methodology and results of teaching an entire engineering course using challenge-based instruction. The challenges consisted of eight biomechanics multimedia learning modules developed by the authors as part of a broader NSF educational coalition. The biomechanics modules were presented in an undergraduate mechanical(More)
And those who helped them through tough times iii ACKNOWLEDGEMENTS Many individuals and organizations, through a variety of financial, professional, and personal contributions, made this work possible. enhancement award, funded equipment that enabled two additional beds to be equipped with the SIMON (Signal Interpretation and Monitoring) system. A Harold(More)
ACKNOWLEDGEMENTS First and foremost, I would like to thank my advisor and mentor Dr. Michael I. Miga. This work and my Ph.D. career would not have been possible but for his continued support. I would also like to thank him for being patient with my mistakes over the last few years. He continues to be a source of encouragement. Dawant and Dr. Thompson for(More)
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