Robert J. Fontana

Jiezhun Gu2
David E Kleiner2
Andrew Stolz2
Huiman Barnhart2
Joseph A Tworek1
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  • Robert J Fontana, Edward A Richley, Anthony J Marzullo, Lance C Beard, Robert W T Mulloy, E J Knight
  • 2002
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  • Nury M. Steuerwald, David M. Foureau, H. James Norton, Jie Zhou, Judith C. Parsons, Naga Chalasani +13 others
  • 2013
UNLABELLED Drug-induced liver injury (DILI) is the most common cause of acute liver failure in the United-States. The aim of the study was to describe serum immune profiles associated with acute DILI, to investigate whether there are profiles associated with clinical features or types of DILI and/or with prognosis, and to assess temporal changes in levels.(More)
UNLABELLED Drug-induced liver injury (DILI) is considered to be a diagnosis of exclusion. Liver biopsy may contribute to diagnostic accuracy, but the histological features of DILI and their relationship to biochemical parameters and outcomes are not well defined. We have classified the pathological pattern of liver injury and systematically evaluated(More)
Hepatic fibrosis is the main determinant of clinical outcomes of chronic hepatitis C. Liver histology is frequently considered the gold standard for assessing hepatic fibrosis. However, liver biopsy is associated with sampling error, interobserver variability, and potential complications. Thus, there is a need for simple, inexpensive, and reliable(More)
BACKGROUND Bupropion is approved for the treatment of mood disorders and as an adjuvant medication for smoking cessation. Bupropion is generally well tolerated and considered safe. Two randomized controlled trials of bupropion therapy for smoking cessation did not report any hepatic adverse events. However, there are three reports of severe but non-fatal(More)