Robert J. Clark

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The MIT Faculty has made this article openly available. Please share how this access benefits you. Your story matters. A scalable, multiplexed ion trap for quantum information processing is fabricated and tested. The trap design and fabrication process are optimized for scalability to small trap size and large numbers of interconnected traps, and for(More)
Bone is the most common site for metastasis in human prostate cancer patients. Skeletal metastases are a significant cause of morbidity and mortality and overall greatly affect the quality of life of prostate cancer patients. Despite advances in our understanding of the biology of primary prostate tumors, our knowledge of how and why secondary tumors(More)
Quantum simulation uses a well-known quantum system to predict the behavior of another quantum system. Certain limitations in this technique arise, however, when applied to specific problems, as we demonstrate with a theoretical and experimental study of an algorithm proposed by Wu, Byrd, and Lidar [Phys. Rev. Lett. 89, 057904(More)
Quantum simulations of spin systems could enable the solution of problems that otherwise require infeasible classical resources. Such a simulation may be implemented using a well-controlled system of effective spins, such as a two-dimensional lattice of locally interacting ions. We propose here a layered planar rf trap design that can be used to create(More)
Host tissue microenvironment plays key roles in cancer progression and colonization of secondary organs. One example is ovarian cancer, which colonizes the peritoneal cavity and especially the omentum. Our research indicates that the interaction of ovarian cancer cells with the omental microenvironment can activate a stress-kinase pathway involving the(More)
Cytochrome P450 (P450) induction is often considered a liability in drug development. Using calibration curve–based approaches, we assessed the induction parameters R 3 (a term indicating the amount of P450 induction in the liver, expressed as a ratio between 0 and 1), relative induction score, C max /EC 50 , and area under the curve (AUC)/F 2 (the(More)
request, provided it is not made publicly available until 12 months after publication. Abstract As the simplest atom, hydrogen has a unique role as a testing ground of fundamental physics. Precision measurements of the hydrogen atomic structure provide stringent tests of current theory, while tritium is an excellent candidate for studies of β-decay and(More)
Overview This research group seeks to understand and develop the experimental and theoretical potential for information processing and communications using the laws of quantum physics. Two fundamental questions motivate our work: (1) How can a large-scale, reliable quantum computer be realized? (2) What new algorithms, cryptographic primitives, and(More)
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