Robert Ian Johnson

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OBJECTIVE To investigate if the use of preoperative platelet function testing (PFT) as part of a transfusion algorithm reduced blood product usage in coronary artery bypass surgery (CABG). DESIGN Prospective, randomized, controlled trial. SETTING A cardiothoracic hospital. PARTICIPANTS 249 patients having CABG surgery. INTERVENTIONS The patients(More)
A potential morbidity of incomplete re-warming following hypothermic cardiopulmonary bypass (CPB) is cardiac arrest. In contrast, attempts to fully re-warm the patient can lead to cerebral hyperthermia. Similarly, rigid adherence to 37.0 degrees C during normothermic CPB may also cause cerebral overheating. The literature demonstrates scant information(More)
Point of care platelet function tests are increasingly used to assess drug-related platelet inhibition prior to cardiac surgery. Numerous devices are available including Thromboelastography (TEG® PlateletMapping™). The latest generation TEG® - the TEG® 6 - has recently been released incorporating a cartridge-based system with a PlateletMapping cartridge. In(More)
INTRODUCTION Viscoelastic methods of estimating fibrinogen measure clot formation under platelet inhibition; these methods are gaining in popularity because of their convenience and speed. The aim of this study was to compare the results of the TEG(®) functional fibrinogen (FF) assay with the Clauss fibrinogen method in a group of patients presenting for(More)
OBJECTIVES To investigate the differences between pre- and post-cardiopulmonary bypass platelet function tests and to examine whether post-bypass tests could predict postoperative bleeding. DESIGN A prospective cohort study. SETTING A tertiary cardiothoracic center. PARTICIPANTS Fifty-four patients presenting for cardiac surgery. INTERVENTIONS Pre-(More)
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