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Loss of Phagocytic and Antigen Cross-Presenting Capacity in Aging Dendritic Cells Is Associated with Mitochondrial Dysfunction
Impaired functionality of dendritic cells (DCs) significantly contributes to decreased adaptive immune responses in aged hosts. The expression of MHC-peptide on the DC surface is the critical firstExpand
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Cross-Presentation of Cell-Associated Antigens by Mouse Splenic Dendritic Cell Populations
Cross-presentation of cell-associated antigens (Ag) plays an important role in the induction of anti-tumor responses, autoimmune diseases, and transplant rejection. While several dendritic cell (DC)Expand
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Adsorbed fibrinogen regulates the behavior of human dendritic cells in a CD18-dependent manner.
The involvement of fibrinogen in inflammation has been considered by many, but the roles of the protein in that process have yet to be fully elucidated. The protein readily coats surfaces and isExpand
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Corticortophin releasing factor 2 receptor agonist treatment significantly slows disease progression in mdx mice
BackgroundDuchenne muscular dystrophy results from mutation of the dystrophin gene, causing skeletal and cardiac muscle loss of function. The mdx mouse model of Duchenne muscular dystrophy is widelyExpand
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Exploring the activated adipogenic niche: Interactions of macrophages and adipocyte progenitors
Adult adipose tissue contains a large supply of progenitors that can renew fat cells for homeostatic tissue maintenance and adaptive growth or regeneration in response to external challenges.Expand
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Extracellular transport of cell-size particles and tumor cells by dendritic cells in culture.
Many particulate materials of sizes approximating that of a cell disseminate after being introduced into the body. While some move about within phagocytic inflammatory cells, others appear to moveExpand
This information is current as Mitochondrial Dysfunction Dendritic Cells Is Associated with Cross-Presenting Capacity in Aging Loss of Phagocytic and Antigen
Impaired functionality of dendritic cells (DCs) significantly contributes to decreased adaptive immune responses in aged hosts. The expression of MHC-peptide on the DC surface is the critical firstExpand
Modulation of Human Dendritic Cell Activity by Adsorbed Fibrin(ogen)
_________________________________________________________________iii Acknowledgements_______________________________________________ v Table of