Learn More
In the National Heart, Lung and Blood Institute Type II Coronary Intervention Study, patients with Type II hyperlipoproteinemia and coronary artery disease (CAD) were placed on a low-fat, low-cholesterol diet and then were randomly allocated to receive either 6 g cholestyramine four times daily or placebo. This double-blind study evaluated the effects of(More)
Lipoprotein mass concentrations were measured by analytical ultracentrifugation in a subset of 57 hypercholesterolaemic male participants in the National Heart, Lung, and Blood Institute Type II Coronary Intervention Study. 2-year changes in levels of intermediate-density lipoproteins (IDL) of flotation rate 12-20 were strongly predictive of progression of(More)
20 male and female patients with type II hyperlipoproteinaemia and 10 normal male and female subjects were fed for 11--15 days a eucaloric diet containing less than 300 mg cholesterol with a polyunsaturated to saturated fatty-acid ratio of about 2.0. Male subjects and patients and female patients showed statistically significant decreases in plasma total(More)
Plasma-high-density-lipoprotein (H.D.L.) cholesterol concentrations are lower in patients with coronary-artery disease than in control subjects. In an investigation of the relationship of H.D.L. cholesterol to other lipid and lipoprotein parameters in normal and hyperlipoproteinaemic subjects inverse correlations were found between H.D.L. cholesterol and(More)
THIS PRESENTATION deals with what Dr. Jeremiah Stamler called "Levy's arrow" (fig. 1), which depicts the involvement of the National Heart, Lung, and Blood Institute (NHLBI) in the bio-medical research continuum. I shall discuss this continuum , together with the role of the NHLBI and its Advisory Council in making assessments, assigning priorities and(More)
THIS PRESENTATION deals with what Dr. Jeremiah Stamler called "Levy's arrow" (fig. 1), which depicts the involvement of the National Heart, Lung, and Blood Institute (NHLBI) in the bio-medical research continuum. I shall discuss this continuum , together with the role of the NHLBI and its Advisory Council in making assessments, assigning priorities and(More)
  • 1