Robert Huber

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We demonstrate in vivo choriocapillaris and choroidal microvasculature imaging in normal human subjects using optical coherence tomography (OCT). An ultrahigh speed swept source OCT prototype at 1060 nm wavelengths with a 400 kHz A-scan rate is developed for three-dimensional ultrahigh speed imaging of the posterior eye. OCT angiography is used to image(More)
Provisioning of ecosystem services (ES) in mountainous regions is predicted to be influenced by i) the direct biophysical impacts of climate change, ii) climate mediated land use change, and iii) socioeconomic driven changes in land use. The relative importance and the spatial distribution of these factors on forest and agricultural derived ES, however, is(More)
The first theoretical model of Fourier domain mode locking operation is presented. A specially tailored dynamic equation in a moving spectral reference frame is derived, enabling efficient numerical treatment, despite the broad laser spectrum and the extremely long cavity. The excellent agreement of the presented theory with experiment over a wide range of(More)
PURPOSE To demonstrate ultrahigh-speed optical coherence tomography (OCT) imaging of the retina and optic nerve head at 249,000 axial scans per second and a wavelength of 1060 nm. To investigate methods for visualization of the retina, choroid, and optic nerve using high-density sampling enabled by improved imaging speed. METHODS A swept-source OCT(More)
We describe buffered Fourier domain mode locking (FDML), a technique for tailoring the output and multiplying the sweep rate of FDML lasers. Buffered FDML can be used to create unidirectional wavelength sweeps from the normal bidirectional sweeps in an FDML laser without sacrificing sweep rate. We also investigate the role of the laser source in dynamic(More)
Optical coherence tomography (OCT) is a rapidly emerging imaging modality that can provide non-invasive, cross-sectional, high-resolution images of tissue morphology in situ and in real-time. In the present series of studies, we used a high-speed OCT imaging system equipped with a frequency-swept laser light source (1.3 mum wavelength) to study living(More)
We analyze the benefits and problems of in vivo optical coherence tomography (OCT) imaging of the human retina at A-scan rates in excess of 1 MHz, using a 1050 nm Fourier-domain mode-locked (FDML) laser. Different scanning strategies enabled by MHz OCT line rates are investigated, and a simple multi-volume data processing approach is presented. In-vivo OCT(More)
We report on a Fourier Domain Mode Locked (FDML) wavelength swept laser source with a highly linear time-frequency sweep characteristic and demonstrate OCT imaging without k-space resampling prior to Fourier transformation. A detailed theoretical framework is provided and different strategies how to determine the optimum drive waveform of the(More)
Mountain ecosystems provide a broad range of ecosystem services (ES). Trade-offs between different ES are an important aspect in the assessment of future sustainable land-use. Management of ES in mountain regions must confront the challenges of spatial and temporal heterogeneity, and interaction with structural changes in agriculture and forestry. Using a(More)
We present a novel method for low noise, high-speed, real-time spectroscopy to monitor molecular absorption spectra. The system is based on a rapidly swept, narrowband CW Fourier-domain mode-locked (FDML) laser source for spectral encoding in time and an optically time-multiplexed split-pulse data acquisition system for improved noise performance and(More)