Robert Hermans

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In the head and neck, squamous cell carcinoma is one of the most common tumour types. Currently, the primary imaging modalities for initial locoregional staging are computed tomography and-to a lesser extent-magnetic resonance imaging, whilst [(18)F]fluorodeoxyglucose (FDG) positron emission tomography has additional value in the detection of subcentimetric(More)
BACKGROUND Several parameters of the tumor microenvironment, such as hypoxia, inflammation and angiogenesis, play a critical role in tumor aggressiveness and treatment response. A major question remains if these markers can be used to stratify patients to certain treatment protocols. The purpose of this study was to investigate the inter-relationship and(More)
INTRODUCTION The aim of this study is to assess the geometric accuracy of diffusion weighted (DW)-MRI by quantification of geometric distortions in the gross tumor volume (GTV) in head and neck (HN) cancer. MATERIALS & METHODS A retrospective analysis was performed on the data of 23 patients (with 24 lesions). For these patients, magnetic field maps and(More)
To evaluate the efficacy of a gradient-echo sequence (3DFT-CISS) in the diagnosis of acoustic neuromas, two independent observers twice reviewed the images of the temporal bones of 83 patients. Contrast-enhanced T1-weighted spin echo images were used as the reference, showing 18 acoustic neuromas, including 5 purely intracanalicular and one(More)
OBJECTIVES To determine the reliability of reformatted 2D-CT for pre-operative planning of implant placement. METHODS One hundred consecutive partially or fully edentate patients underwent 2-D reformatted CT pre-operative planning and subsequent implant placement. The number, site and size of the implants, the available bone height and anatomical(More)
The activity of single motor units (MUs) of the orbicularis oculi muscle was recorded in normal volunteers. While the subject maintained a constant firing rate, electrical stimuli were applied to the ipsilateral supraorbital nerve. Peristimulus histograms were constructed showing 2 periods of discharge accumulation at times corresponding to the R1 and R2(More)
Sophisticated imaging methods, such as computed tomography, magnetic resonance imaging and positron emission tomography, play an increasingly important role in the management of head and neck cancer. Pretreatment imaging findings have predictive value for patient outcome, independently from the currently used TNM classification, and may be used to tailor(More)
PURPOSE To determine how the ADC value of parotid glands is influenced by the choice of b-values. MATERIALS AND METHODS In eight healthy volunteers, diffusion-weighted echo-planar imaging (DW-EPI) was performed on a 1.5 T system, with b-values (in seconds/mm2) of 0, 50, 100, 150, 200, 250, 300, 500, 750, and 1000. ADC values were calculated by two(More)
The aim of this study was to evaluate the feasibility of functional MR imaging (fMRI) at 1.5 T, exploiting blood oxygenation level-dependent (BOLD) contrast, for detecting changes in whole-tumour oxygenation induced by carbogen (5% CO2+95% O2) inhalation of the host. Adult WAG/Rij rats with rhabdomyosarcomas growing subcutaneously in the lower flank were(More)