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Livers of dogs which were microfilaremic due to infection with Dirofilaria immitis were studied after the administration of diethylcarbamazine. Most dogs had a severe shock-like clinical reaction. The main hepatic features were congestion and hemorrhage around the central vein and irregularly scattered foci of inflammation. The severity of the vascular(More)
OBJECTIVE To test the possible inhibitory effect of allopurinol on reperfusion injury, caused by oxygen-derived free radicals, of sheep large intestine. DESIGN An ultrastructural study on caecal tissues from control and treated groups. ANIMALS Fifty sheep in four ischaemic and reperfused (treatment) groups and one control group. Three of the treatment(More)
A 13-year-old Standardbred stallion presented with a unilateral mucopurulent nasal discharge and airway obstruction was found to have an extensive cryptococcal nasal granuloma. Treatment was not attempted. The stallion was destroyed 26 months later having completed 2 successful breeding seasons. The granuloma had gradually increased in size and almost(More)
The main features of Cryptococcus neoformans infection in 6 dogs, all of which were of large breed, were central nervous system involvement in all cases and diversity of the initial presenting signs. The respiratory tract was affected in one case, but the bronchopneumonia did not appear to be of cryptococcal origin. Immunosuppressive factors and other(More)
Dead adult D. immitis were inserted into the pulmonary arteries of 10 healthy pups, five of which were given a crude antigenic extract of D. immitis subcutaneously. Two dogs, one from each group were then killed 1, 3, 5, 7 and 9 days after the insertion of filariae and the associated pulmonary artery pathology examined. Microscopically, haemorrhage was(More)
Severe lameness attributed to osteochondrosis is described in an extensively managed Brahman herd grazing on improved native pasture. Clinical signs were observed in five animals, three of which were necropsied. The most prominent lesions were in the elbow and stifle joints. There were multiple fissuring and ulceration of thickened articular cartilage with(More)
Thirteen cases of lymphoid neoplasia were examined in koalas from New South Wales and Queensland. Haematological and biochemical data were collected from 2 cases while all were subjected to detailed necropsies. Affected koalas were adults of both sexes and the disease had a variable time course. The 2 koalas examined haematologically were leukaemic. On a(More)