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PURPOSE To evaluate the efficacy of three hormonal manipulations in the palliation of chemoresistant ovarian cancer, and to analyze the results in the light of other clinical trials. PATIENTS AND METHODS Three sequential phase II trials were performed in patients with refractory epithelial ovarian carcinoma, using high-dose megestrol acetate (800 mg/d for(More)
Existing research understates the benefits that can be obtained from inlining and cloning, especially when guided by profile information. Our implementation of inlining and cloning yields excellent results on average and very rarely lowers performance. We believe our good results can be explained by a number of factors: inlining at the intermediate-code(More)
INTRODUCTION Racial/ethnic minority communities are at increasingly high risk for chronic diseases related to obesity. Access to stores that sell affordable, nutritious food is a prerequisite for adopting a healthful diet. The objective of this study was to evaluate food access, availability, and affordability in 3 nonoverlapping but similar low-income(More)
The vast majority of dry cleaners worldwide use the toxic chemical perchloroethylene (PCE), which is associated with a number of adverse health and environmental impacts. Professional wet cleaning was developed as a nontoxic alternative to PCE dry cleaning but has not been widely adopted as substitute technology. In the greater Los Angeles, CA, region, a(More)
is one of ten regional units mandated by Congress and established in Fall I988 to support research, education, and training in surface transportation. The UC Center serves federal Region IX and is supported by matching grants from the U.S. Department of Transportation, the California Department of Transportation (Caltrans), and the University. Based on the(More)
This paper discusses opportunities to promote pollution prevention technologies through public policy, describing the case of dry cleaning. The crisis in dry cleaning is associated with the industry's reliance on perchloroethylene (PCE), the chemical cleaning solvent used by the vast majority of cleaners. The limits to the current pollution control or(More)