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In the growing follicle, communication between the oocyte and its surrounding follicular cells is essential for normal oocyte and follicular development. Maturation of the fully grown oocyte in vivo is associated with the loss of cumulus cell-oocyte gap junctional communication, preventing entry of meiotic-modulating factors such as cAMP into the oocyte. We(More)
The univariate and multivariate logistic regression model is discussed where response variables are subject to randomized response (RR). RR is an interview technique that can be used when sensitive questions have to be asked and respondents are reluctant to answer directly. RR variables may be described as misclassified categorical variables where(More)
Developmental competence of in vitro matured (IVM) oocytes needs to be improved and this can potentially be achieved by adding recombinant bone morphogenetic protein 15 (BMP15) or growth differentiation factor (GDF9) to IVM. The aim of this study was to determine the effect of a purified pro-mature complex form of recombinant human BMP15 versus the(More)
31 32 In the growing follicle, communication between the oocyte and its surrounding follicular 33 cells is essential for normal oocyte and follicular development. Maturation of the fully-34 grown oocyte in vivo is associated with the loss of cumulus cell-oocyte gap junctional 35 communication, preventing entry of meiotic-modulating factors such as cAMP into(More)
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