Robert Gie

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Childhood tuberculosis (TB) is a preventable and curable infectious disease that remains overlooked by public health authorities, health policy makers and TB control programmes. Childhood TB contributes significantly to the burden of disease and represents the failure to control transmission in the community. Furthermore, the pool of infected children(More)
Improving the management of childhood tuberculosis within national tuberculosis programmes: research priorities based on a literature review Members of subgroup on childhood TB 1 (reviewed and endorsed the document) The designations employed and the presentation of the material in this publication do not imply the expression of any opinion whatsoever on the(More)
Until recently, little attention has been given to chronic lung disease (CLD) in HIV-infected children. As the HIV epidemic matures in sub-Saharan Africa, adolescents who acquired HIV by vertical transmission are presenting to health services with chronic diseases. The most common is CLD, which is often debilitating. This review summarizes the limited data(More)
OBJECTIVE To evaluate the pneumonia specific case fatality rate over time following the implementation of a Child Lung Health Programme (CLHP) within the existing government health services in Malawi to improve delivery of pneumonia case management. METHODS A prospective, nationwide public health intervention was studied to evaluate the impact on(More)
The chest radiograph (CXR) is considered a key diagnostic tool for pediatric tuberculosis (TB) in clinical management and endpoint determination in TB vaccine trials. We set out to compare interrater agreement for TB diagnosis in western Kenya. A pediatric pulmonologist and radiologist (experts), a medical officer (M.O), and four clinical officers (C.Os)(More)
OBJECTIVE To investigate recognised co-morbidities and clinical management associated with inpatient pneumonia mortality in Malawian district hospitals. METHODS Prospective cohort study, of patient records, carried out in Malawi between 1st October 2000 and 30th June 2003. The study included all children aged 0-59 months admitted to the paediatric wards(More)
Airway deformation and stenosis can be key signs of pathology such as lymphadenopathy. This study presents a local airway point distribution model (LA-PDM) to automatically analyse regions of the airway tree in CT scans and identify abnormal airway deformation. In our method, the airway tree is segmented and the centreline identified from each chest CT(More)
Clinical signs of paediatric pulmonary tuberculosis (TB) include stenosis and deformation of the airways. This paper presents two methods to analyse airway shape and detect airway pathology from CT images. Features were extracted using (1) the principal components of the airway surface mesh and (2) branch radius and orientation features. These methods were(More)
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