Robert G. Rogers
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Background Occipital nerve (ON) injections with corticosteroids and/or local anesthetics have been employed for the acute and preventive treatment of migraine for decades. However, to date there is… Expand
This chapter discusses analytic and algorithmic results for computational protein structure prediction by protein sequence–structure alignment, an approach also known as “protein threading.” The… Expand
Low phase noise microwave oscillator design the active circuit oscillator element the resonator circuit oscillator element combining the elements - the oscillator performance evaluation mechanics.
A rigorous Bayesian analysis is presented that unifies protein sequence-structure alignment and recognition. Given a sequence, explicit formulae are derived to select (1) its globally most probable… Expand
We present a protein fold-recognition method that uses a comprehensive statistical interpretation of structural Hidden Markov Models (HMMs). The structure/fold recognition is done by summing the… Expand
We present a knowledge-based threading scoring function that exploits the information about protein structure contained in residue packing/neighbor preferences. The proposed algorithm eliminates the… Expand
Pairwise contact potentials have a long, successful history in protein structure prediction. They provide an easily-estimated representation of many attributes of protein structures, such as the… Expand
A short review of the threading approach to protein structure prediction, including presentation of some open statistical problems. Also discussed is one of the likely sources of the current limited… Expand
The logic behind the threading approach to the prediction of an amino acid sequence`s expected three-dimensional fold is almost seductively simple, if not obvious. In practice, however, the threading… Expand
We present a new procedure for optimization of a threading scoring function. A scoring function is usually formulated in terms of the structural environment states that describe the protein fold… Expand