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OBJECTIVE To identify risk factors for suspected acute endophthalmitis after cataract surgery. DESIGN Population-based retrospective cohort. PARTICIPANTS Administrative data from more than 440,000 consecutive cataract surgeries in Ontario, Canada, from April 1, 2002, to March 31, 2006. METHODS Consecutive physician billing claims for cataract surgery(More)
PURPOSE A review of treat-and-extend regimens (TERs) with intravitreal anti-vascular endothelial growth factor agents in retinal diseases. METHODS There is a lack of consensus on the definition and optimal application of TER in clinical practice. This article describes the supporting evidence and subsequent development of a generic algorithm for TER(More)
BACKGROUND/AIMS A retrospective consecutive case series to evaluate the efficacy of re-operation in patients with persistent or recurrent idiopathic full-thickness macular hole after initial surgery with internal limiting membrane peel (ILM). METHODS 491 patients underwent surgery for full-thickness macular hole from January 2004 to November 2007.(More)
BACKGROUND Insulin-dependent diabetes mellitus (IDDM) and eating disorders are relatively common among young women in North America. Their coexistence could lead to poor metabolic control and an increased risk of the microvascular complications of IDDM. METHODS We studied 91 young women with IDDM at base line and four to five years later to determine the(More)
Twenty-five micrograms of human recombinant tissue plasminogen activator (tPA) was injected intracamerally into the eyes of three aphakic patients who developed severe intraocular fibrin formation within 24 hours after vitrectomy surgery. Fluid obtained from gas-fluid exchange specimens taken 24 hours after tPA injection was analyzed for tPA by an(More)
PURPOSE To report the incidence of endophthalmitis in association with different antibiotic prophylaxis strategies after intravitreal injections of anti-vascular endothelial growth factors and triamcinolone acetonide. DESIGN Retrospective, comparative case series. PARTICIPANTS Fifteen thousand eight hundred ninety-five intravitreal injections (9453(More)
BACKGROUND The most desirable effect following cataract surgery in the presence of age-related macular degeneration (AMD) is to obtain an improvement in distance resolution acuity, and the only optical solution to this is the use of telescopic magnification. The purpose of the study was to develop and verify the clinical utility of inducing low-grade(More)
BACKGROUND The Heidelberg retina tomograph, a scanning laser ophthalmoscope that uses confocal optics to provide high resolution of images, is able to scan the retina in three dimensions to obtain quantitative topographic measurements. The authors evaluated its usefulness for measuring macular lesions by determining the reproducibility of its topographic(More)
OBJECTIVE To compare the efficacy of retrobulbar and peribulbar anesthetic techniques for vitreoretinal surgical procedures. DESIGN Prospective, randomized, double-blind study. SETTING A large university teaching hospital. PARTICIPANTS One hundred sixteen consecutive patients who were scheduled for vitreoretinal surgical procedures. METHODS Patients(More)