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- Kasey C. Vickers, Brian T. Palmisano, Bassem M. Shoucri, Robert D. Shamburek, Alan T Remaley
- Nature Cell Biology
- 2011
Circulating microRNAs (miRNA) are relatively stable in plasma and are a new class of disease biomarkers. Here we present evidence that high-density lipoprotein (HDL) transports endogenous miRNAs and… (More)
- Barbara B Biesecker, James C. Mullikin, +20 authors Eric D. Green
- Genome research
- 2009
ClinSeq is a pilot project to investigate the use of whole-genome sequencing as a tool for clinical research. By piloting the acquisition of large amounts of DNA sequence data from individual human… (More)
- Annie M. Bérard, Bernhard Foeger, +8 authors Silvia Santamarina-Fojo
- Nature Medicine
- 1997
A subset of patients with high plasma HDL concentration have enhanced rather than reduced atherosclerosis. We have developed a new transgenic mouse model overexpressing human lecithin-cholesteryl… (More)
- Judy T. Chen, Robert M Wesley, Robert D. Shamburek, Frank Pucino, Gyorgy Csako
- Pharmacotherapy
- 2005
STUDY OBJECTIVE
To compare the efficacy and safety of plant sterols and stanols as well as policosanol in the treatment of coronary heart disease, as measured by a reduction in low-density… (More)
- Bernhard Foeger, Maureen R Chase, +9 authors Silvia Santamarina-Fojo
- The Journal of biological chemistry
- 1999
Expression of human lecithin cholesterol acyltransferase (LCAT) in mice (LCAT-Tg) leads to increased high density lipoprotein (HDL) cholesterol levels but paradoxically, enhanced atherosclerosis. We… (More)
- Bernhard Foeger, Silvia Santamarina-Fojo, Robert D. Shamburek, Camila Parrot, Gregory Talley, H. Bryan Brewer
- The Journal of biological chemistry
- 1997
In vitro studies have shown that plasma phospholipid transfer protein (PLTP) converts isolated human high density lipoprotein-3 (HDL3) into larger HDL particles and generates lipid-poor apoA-I… (More)
- Marcelo José Andrade Oliveira, Hendrick E van Deventer, +10 authors Alan T Remaley
- Clinica chimica acta; international journal of…
- 2013
BACKGROUND
Low-density lipoprotein cholesterol (LDL-C) is often calculated (cLDL-C) by the Friedewald equation, which requires high-density lipoprotein cholesterol (HDL-C) and triglycerides (TG).… (More)
- W. Greg Miller, Gary L. Myers, +14 authors Alan T Remaley
- Clinical chemistry
- 2010
BACKGROUND
Methods from 7 manufacturers and 1 distributor for directly measuring HDL cholesterol (C) and LDL-C were evaluated for imprecision, trueness, total error, and specificity in nonfrozen… (More)
- Arnon Blum, Robert D. Shamburek
- Atherosclerosis
- 2009
Statins have been demonstrated to significantly affect the prognosis and outcome of patients with risk factors to atherosclerosis (in primary and secondary prevention trials). Several clinical and… (More)
- Ronald M. Summers, P. L. Choyke, +5 authors Robert D. Shamburek
- Journal of computer assisted tomography
- 2001
PURPOSE
The thoracic aorta is an important site of atherosclerotic disease in patients with homozygous familial hypercholesterolemia (HFH). Thoracic aortic atherosclerosis in patients with HFH was… (More)