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- Daniel J Klionsky, Fábio Camargo Abdalla, +497 authors Motoni Kadowaki
- Autophagy
- 2012
In 2008 we published the first set of guidelines for standardizing research in autophagy. Since then, research on this topic has continued to accelerate, and many new scientists have entered the… (More)
- Cristen J. Willer, Serena Sanna, +47 authors Gonçalo R. Abecasis
- Nature Genetics
- 2008
To identify genetic variants influencing plasma lipid concentrations, we first used genotype imputation and meta-analysis to combine three genome-wide scans totaling 8,816 individuals and comprising… (More)
- J. - C. Lambert, Carla A. Ibrahim-Verbaas, +179 authors Philippe Amouyel
- Nature Genetics
- 2013
Eleven susceptibility loci for late-onset Alzheimer's disease (LOAD) were identified by previous studies; however, a large portion of the genetic risk for this disease remains unexplained. We… (More)
- Daniel J Klionsky, Kotb Abdelmohsen, +497 authors Luciana Dini
- Autophagy
- 2016
- Sarah Lewington, Robert Clarke, Nawab Qizilbash, Richard Peto, Rory Collins
- Lancet
- 2002
BACKGROUND
The age-specific relevance of blood pressure to cause-specific mortality is best assessed by collaborative meta-analysis of individual participant data from the separate prospective… (More)
- Sekar Kathiresan, Cristen J. Willer, +58 authors L. Adrienne Cupples
- Nature Genetics
- 2009
Blood low-density lipoprotein (LDL) cholesterol, high-density lipoprotein (HDL) cholesterol and triglyceride levels are risk factors for cardiovascular disease. To dissect the polygenic basis of… (More)
- Sarah Lewington, Gary George Whitlock, +6 authors Rory Collins
- Lancet
- 2007
BACKGROUND
Age, sex, and blood pressure could modify the associations of total cholesterol (and its main two fractions, HDL and LDL cholesterol) with vascular mortality. This meta-analysis combined… (More)
- Robert Clarke, John F. Peden, +20 authors Martin Farrall
- The New England journal of medicine
- 2009
BACKGROUND
An increased level of Lp(a) lipoprotein has been identified as a risk factor for coronary artery disease that is highly heritable. The genetic determinants of the Lp(a) lipoprotein level… (More)
- Christopher H. Newton-Cheh, Toby Johnson, +155 authors Patricia B. Munroe
- Nature Genetics
- 2009
Elevated blood pressure is a common, heritable cause of cardiovascular disease worldwide. To date, identification of common genetic variants influencing blood pressure has proven challenging. We… (More)
- Panagiotis Deloukas, Stavroula Kanoni, +180 authors Nilesh J. Samani
- Nature Genetics
- 2013
Coronary artery disease (CAD) is the commonest cause of death. Here, we report an association analysis in 63,746 CAD cases and 130,681 controls identifying 15 loci reaching genome-wide significance,… (More)