Learn More
There is still a low level of clinical awareness regarding Legionnaires' disease 25 years after it was first detected. The causative agents, legionellae, are freshwater bacteria with a fascinating ecology. These bacteria are intracellular pathogens of freshwater protozoa and utilize a similar mechanism to infect human phagocytic cells. There have been major(More)
The bioterrorism-associated human anthrax epidemic in the fall of 2001 highlighted the need for a sensitive, reproducible, and specific laboratory test for the confirmatory diagnosis of human anthrax. The Centers for Disease Control and Prevention developed, optimized, and rapidly qualified an enzyme-linked immunosorbent assay (ELISA) for immunoglobulin G(More)
  • D B Jernigan, J Hofmann, M S Cetron, C A Genese, J P Nuorti, B S Fields +7 others
  • 1996
BACKGROUND Outbreaks of travel-related Legionnaires' disease present a public-health challenge since rapid, sensitive, and specific diagnostic tests are not widely used and because detection of clusters of disease among travellers is difficult. We report an outbreak of Legionnaires' disease among cruise ship passengers that occurred in April, 1994, but that(More)
In response to the emergence of severe acute respiratory syndrome (SARS), the United States established national surveillance using a sensitive case definition incorporating clinical, epidemiologic, and laboratory criteria. Of 1,460 unexplained respiratory illnesses reported by state and local health departments to the Centers for Disease Control and(More)
BACKGROUND From June to November 2005, 18 cases of community-acquired Legionnaires' disease (LD) were reported in Rapid City South Dakota. We conducted epidemiologic and environmental investigations to identify the source of the outbreak. METHODS We conducted a case-control study that included the first 13 cases and 52 controls randomly selected from(More)
Legionella-like amebal pathogens (LLAPs) are nonculturable, protozoonotic, gram-negative bacilli. They were named LLAPs because of their ability to infect and multiply intracellularly within amebae (Figure 1) in the same way that legionellae infect and multiply in protozoa and human alveolar mac-rophages (1-3). However, unlike other known legionellae, LLAPs(More)
Using oral swab samples to detect West Nile virus in dead birds, we compared the Rapid Analyte Measurement Platform (RAMP) assay with VecTest and real-time reverse-transcriptase-polymerase chain reaction. The sensitivities of RAMP and VecTest for testing corvid species were 91.0% and 82.1%, respectively.
  • M D Fenstersheib, M Miller, C Diggins, S Liska, L Detwiler, S B Werner +3 others
  • 1990
An outbreak of Pontiac fever occurred among 34 of 56 people attending conferences at a hotel in Santa Clara County, California, in 1988. Two groups had an acute febrile upper respiratory illness, with a mean attack rate of 82% and a mean incubation period of 56 hours. Symptoms resolved spontaneously within 5 days. Legionella anisa, which had not previously(More)
Theoretical studies have shown the potential scientific value of multi-spacecraft radio tomographic imaging of the magnetosphere. The <10 RE WIND perigee passes during August 2000 afforded a unique opportunity to test and verify the capabilities of radio tomography by measuring interspacecraft electromagnetic wave propagation parameters using the Radio(More)