Robert B. Drysdale

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A randomised controlled trial has been performed in 150 patients undergoing biliary operations to determine whether an antibiotic which is excreted almost entirely in bile (rifamide) is to be preferred to one having satisfactory serum levels only (gentamicin). Patients were allocated to one of three groups: 50 received gentamicin, 50 received rifamide, and(More)
1. A procedure is described for the purification of l-histidinol dehydrogenase (l-histidinol-NAD oxidoreductase, EC 1.1.1.23) from Neurospora crassa. 2. The enzyme, as purified, has a sedimentation coefficient, S(20), of 7.1s and a molecular weight of 81 000. Considerable variation is possible in the state of polymerization of the enzyme, giving rise to(More)
OBSERVATIONS from a number of different fields suggest that di-(2-chloroethyl) sulphide (sulphur mustard, H) and methyl-di-(2-chloroethyl)amine (nitrogen mustard, HN2) have a specific effect on the process of nuclear division (Philips, 1950). In view of the importance of deoxyribonucleic acid (DNA) in cell division, it might be expected that sulphur and(More)
A single tetrad in which one genetical marker had segregated irregularly was analyzed genetically by outcrossing each culture derived from the tetrad to other haploid clones. Regular segregation in the resultant hybrids indicated that the cultures were all haploid. The original ascus was tetratype proving that all four nuclei had survived after reduction.(More)
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