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Dietary restriction has been shown to have several health benefits including increased insulin sensitivity, stress resistance, reduced morbidity, and increased life span. The mechanism remains unknown, but the need for a long-term reduction in caloric intake to achieve these benefits has been assumed. We report that when C57BL6 mice are maintained on an(More)
The mechanisms underlying the ability of caloric restriction (CR) to extend life span and enhance stress responsiveness remain elusive. Progress in this area has been slow due to the complexities of using animals for CR studies and assessing life span as the measure of CR effectiveness. It is therefore of great interest to develop in vitro models of CR.(More)
The obvious benefits for team collaboration achieved through the use of Electronic Meeting Systems (EMS), do not appear to be so obvious on an organizational scale. After years of trying, there are relatively few published reports of rapid and broad adoption and diffusion of this technology. The broader class of Group Support System (GSS) technologies, that(More)
OBJECTIVE To investigate health gain and its predictors during inpatient and associated day patient treatment. METHOD Consecutive admissions to two inpatient units for children and young adolescents in northwest England were studied (N = 55). Ascertainments were made from multiple perspectives, including family, teacher, clinician, and an independent(More)
The increasing investment in technology for training and learning in organizations underscores the fundamental importance for researchers to understand and investigate technology-mediated learning (TML). Currently, a great deal of Information Systems (IS) training for both IS professionals and end-users has a TML component. With the continuing growth of TML(More)
Imagine yourself seated in a conference room for another design team meeting to develop the logical systems design of a new information system. User representatives and other system analysts assigned to the project are seated around a horseshoe table. In previous meetings the team has charted a general data flow diagram identifing the processes, objects,(More)
This paper presents a field study of using an Electronic Meeting System (EMS) to support actual meetings in four different time and place modes within a large company. The meeting descriptions provide concrete case illustrations of how different meeting modes can work, what types of effects can occur, and factors which contribute to success. Analysis of(More)