Robert A Tell

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BACKGROUND Evidence-based medicine is valuable to the extent that the evidence base is complete and unbiased. Selective publication of clinical trials--and the outcomes within those trials--can lead to unrealistic estimates of drug effectiveness and alter the apparent risk-benefit ratio. METHODS We obtained reviews from the Food and Drug Administration(More)
Epithelial cells lining the adult colon do not normally express gastrin-releasing peptide (GRP) or its receptor (GRPR). In contrast, GRP/GRPR can be aberrantly expressed in human colorectal cancer (CRC) including Caco-2 cells. We have previously shown that GRPR activation results in the up-regulation of HP1β, an epigenetic modifier of gene transcription.(More)
Epithelial cells lining the adult colon do not normally express gastrin-releasing peptide (GRP) or its receptor (GRPR). In contrast, GRP/GRPR can be aberrantly expressed in colon cancer where they are associated with improved patient survival rates. However, the mechanism of action whereby these proteins mediate their beneficial effects is not known.(More)
summary) Translate [unavailable for this document] Full text Back to document Selective Publication of Antidepressant Trials and Its Influence on Apparent Efficacy Turner, Erick H, MD; Matthews, Annette M, MD; Linardatos, Eftihia; Tell, Robert A, LCSW; Rosenthal, Robert. The New England Journal of Medicine 358. 3 (Jan 17, 2008): 252-60. Get it at Duke(More)
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