Robert A LaMothe

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The applicability of orthogonal expansions (singular-value decomposition, Karhunen-Loève transform and principal-component analysis) for the purpose of identifying source distributions associated with definite electrophysiological events in the heart and brain is explored with a current dipole source model. By definition, the expansion eigenvectors are(More)
Current treatments to control pathological or unwanted immune responses often use broadly immunosuppressive drugs. New approaches to induce antigen-specific immunological tolerance that control both cellular and humoral immune responses are desirable. Here we describe the use of synthetic, biodegradable nanoparticles carrying either protein or peptide(More)
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