Robert A. Griffin

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The authors examined continued neuroleptic exposure following inpatient treatment of mania with neuroleptics and lithium through structured chart review of 40 consecutive patients. At discharge, patients were receiving a mean of 793 mg/day (SD = 695) chlorpromazine equivalents; 6 months later they were receiving a mean of 634 mg/day (SD = 684). This(More)
BACKGROUND Although the chronic use of neuroleptic medications is generally discouraged in patients with bipolar disorder, data on the actual extent of this practice are relatively scarce. METHOD All bipolar patients receiving treatment at the Connecticut Mental Health Center on September 1, 1994, were identified through a computerized administrative(More)
Primary and metastatic malignant fibrous histiocytoma of the alimentary tract is uncommon, even though it is the most frequently diagnosed malignant soft tissue tumor in adults. In this report, we describe a patient with a left gluteal malignant fibrous histiocytoma who had intermittent melena and hematochezia attributed to colon metastases, 1 yr after(More)
PURPOSE Cis-platinum and radiation in combination are current organ preservation treatment strategies for head and neck cancer. Their individual ototoxicity has been investigated, with recent demonstration of ototoxicity in clinical studies. Currently, no ototoxicity studies have been performed in animals receiving similar schedules of radiation or(More)
We report a theoretical investigation of the crosstalk performance of photonic code-division multiple-access (CDMA) networks that are based on coherent matched filtering of optical pulses. We describe the importance of time gating in the reduction of noise in spread-time CDMA schemes. We give guidelines for the selection of codes in coherent matched(More)
Interleukin-13 (IL-13) sequentially binds to IL-13Ralpha1 and IL-4Ralpha forming a high affinity signalling complex. This receptor complex is expressed on multiple cell types in the airway and signals through signal transducer and activator of transcription factor-6 (STAT-6) to stimulate the production of chemokines, cytokines and mucus. Antibodies have(More)
Three aborted canine fetuses were submitted to the Animal Health Diagnostic Center at Cornell University in November 2011 and September 2012 for diagnostic workups to determine the causes of the reproductive difficulties. Histological assessments of the sampled tissues were inconclusive due to the autolysis. Tests to detect bacterial causes of the abortions(More)
OBJECTIVES Chronic stress was previously reported to play a role in the development of oral cancer, yet the correlation between stressors and oral cancer progression is not well understood. MATERIALS AND METHODS We implanted human oral cancer cell line CAL 27 in nude mice to investigate the effects of chronic stress on tumor growth, and designed a(More)