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OBJECTIVE Living-donor lobar lung transplantation offers an alternative for patients with a life expectancy of less than a few months. We report on our intermediate results with respect to recipient survival, complications, pulmonary function, and hemodynamic reserve. METHODS Thirty-eight living-donor lobar lung transplants were performed in 27 adult and(More)
Upper midline laparotomy in the presence of pulmonary failure is often complicated by a prolonged period of mechanical ventilation postoperatively. We report the successful performance of laparoscopic fundoplication, without ventilatory support, in a woman with end stage pulmonary disease and resting hypercarbia, one month prior to lung transplantation.
Since 1993 a total of 101 living-donor bilateral lung transplants have been performed with acceptable results when compared with those utilizing cadaveric lung grafts. Though most recipients were patients with cystic fibrosis who were rapidly deteriorating, the indications for live-donor lung transplantation have been expanded to include some cystic(More)
Canine venous autografts and allografts were interposed in the femoral and carotid arterial positions in 29 dogs; grafts were harvested at three postoperative intervals (1-2 weeks, 4-6 weeks, and 8-10 weeks) for light and scanning electron (SEM) microscopy and lumenal surface prostacyclin (PGI2) production. Normal veins and arteries were used as controls.(More)
The administration of albumin in the initial resuscitation of shock remains highly controversial. Impaired coagulation in the critically injured patient has recently been added as an argument against the use of supplemental albumin. This study investigated the hemostatic effects of albumin therapy after hemorrhagic shock. Twenty mongrel dogs were bled to a(More)
BACKGROUND Protection of the myocardium during beating heart operations is paramount. The goal of this study is to determine if regional topical hypothermia (RTH) preserves myocardial viability and function during periods of temporary coronary artery occlusion. METHODS Sixteen pigs were divided into two groups (RTH and control). Each group received 40(More)
Lobar transplantation represents a therapeutic option for children and some adults with severe end-stage pulmonary disease. Six patients including two neonates, three children, and one adult underwent lobar transplantation. Ages ranged from 17 days to 21 years. Transplant procedures were unilateral in the neonates and two of the children and bilateral in(More)
BACKGROUND We reviewed our experience with adult living lobar lung transplant (LL) recipients to assess whether size and shape mismatch of the donor organ to the recipient pre-disposes to the development of pleural space problems (PSP). METHODS Eighty-seven LL were performed on 84 adult recipients from 1993 through 2003. Seventy-six patients had cystic(More)
A substantial number of severely injured patients are under the influence of alcohol, making it important to understand the effects of acute alcoholic intoxication on the clotting mechanism. Twenty healthy volunteers ingested commercial liquor over a four-hour period and were observed for another three hours. Peak blood alcohol levels were above 200 mg/dL(More)