Rob S G M Bots

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The aim of this study was to search for the existence of behavioural states in the human fetus and to describe their developmental course. In a longitudinal study, 14 low-risk fetuses were studied at 2-week intervals from 32 weeks of gestation onward. Fetal body movements as well as fetal eye movements, visualized by means of real-time ultrasonic imaging,(More)
OBJECTIVE To describe the annual results in all 13 Dutch in vitro fertilisation (IVF) centres in the period 1996-2000, and to look for possible differences between individual centres and years. DESIGN Retrospective data collection, description and analysis. METHOD The results collected on the website of the Dutch Society of Obstetrics and Gynaecology(More)
OBJECTIVE To present the numbers and results of Dutch IVF treatment from 1996-2005 and to describe trends and differences between centres. DESIGN Retrospective data-collection, description and analysis. METHOD The annual statistics from all Dutch IVF centres covering the years 1996-2005 were collected, described and analysed. RESULTS During this(More)
BACKGROUND Unexplained infertility is one of the most common diagnoses in fertility care. The aim of this study was to evaluate the outcome of current fertility management in unexplained infertility. METHODS In an observational, longitudinal, multicentre cohort study, 437 couples were diagnosed with unexplained infertility and were available for analysis.(More)
The aim of this randomized cross-over study was to determine whether direct intraperitoneal insemination (DIPI) is superior to intrauterine insemination (IUI) in hyperstimulated cycles. The treatment cycles were stimulated with either clomiphene citrate and human menopausal gonadotrophins, or buserelin and human menopausal gonadotrophins. 207 subfertile(More)
Eye movements of the human fetus were detected in utero by means of real-time B-scan and M-mode ultrasonography. In 14 low-risk fetuses studied between 32 weeks menstrual age and term either rapid or slow eye movements or a mixture of both types were detected in 60 +/- 10% (mean +/- SD) of 558 2 min scoring epochs. A comparison of direct echoscopic(More)
In this longitudinal multicentre cohort study, the overall ongoing pregnancy rate after current evidence-based management in male subfertility was studied. All subfertile couples who visited the fertility clinic for the first time between 2002 and 2006, and had male subfertility as a single diagnosis (n = 762 of 2476 couples), were included in this study.(More)
A case report is presented in which a triplet pregnancy ended in an immature delivery of triplet A at 20 weeks gestation, followed by a successful delay in delivery of 49 days of triplets B and C by means of a cervical cerclage and tocolysis. This is the first reported case in which two living infants could be vaginally delivered after a preceding vaginal(More)
Patients suffering from normogonadotrophic anovulation and infertility are initially treated with clomiphene citrate. Those who do not respond to clomiphene citrate usually receive gonadotrophin treatment which is labour-intensive, expensive, and associated with an increased risk of multiple pregnancies and ovarian hyperstimulation syndrome. We treated 22(More)